Intensity modulated radiation therapy (IMRT) versus intensity modulated stereotactic radiation therapy (IMSRT) for children with intraocular retinoblastoma

Details

Serval ID
serval:BIB_E0D579F0BFF1
Type
Inproceedings: an article in a conference proceedings.
Publication sub-type
Poster: Summary – with images – on one page of the results of a researche project. The summaries of the poster must be entered in "Abstract" and not "Poster".
Collection
Publications
Institution
Title
Intensity modulated radiation therapy (IMRT) versus intensity modulated stereotactic radiation therapy (IMSRT) for children with intraocular retinoblastoma
Title of the conference
9th Annual Meeting of the Scientific Association of Swiss Radiation Oncology (SASRO)
Author(s)
Pica A., Munier F., Balmer A., Do H.P., Bressan S., Bulling S., Mirimanoff R.O., Moeckli R.
Address
Basel, Switzerland, March 17-19, 2005
ISBN
0179-7158
Publication state
Published
Issued date
2005
Peer-reviewed
Oui
Volume
181
Series
Strahlentherapie und Onkologie
Pages
144
Language
english
Notes
Document Type: Meeting Abstract
Abstract
Objective: To compare IMSRT with IMRT and stereotactic radiotherapy, in terms of target volume coverage and
critical structure sparing, for the treatment of introcular retinoblastoma.
Material and Methods: IMSRT, IMRT, and conventional stereotactic treatment plans were prepared for a test case; 3-yrs old,
recurrent unilateral retinoblastoma. The planning goal was 95% isodose coverage of the PTV with
minimum dose to the optic nerve, bony orbit and lense. Target conformity (total tissue volume receiving
≥ 80%, 50% and 20% dose), optic nerve volume receiving ≥ 50% dose, and the maximum lense dose
were evaluated.
Results: The central nervous system volume and bony orbit volume encompassed by the 20% and 50% isodoses
respectively, was significantly less for IMRST and stereotactic radiotherapy than for IMRT. Doses to the
lense and lacrimal gland were reduced with IMSRT, but optic nerve sparing was not improved.
Conclusion: Stereotactic treatment is the best method for linac-based treatment of intraocular retinoblastoma.
Compared with conventional stereotactic treatment, IMSRT slightly improves the sparing of organs at
risk.
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Create date
28/04/2008 10:35
Last modification date
20/08/2019 16:05
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