Cardiac sources of embolism and cerebral infarction--clinical consequences and vascular concomitants: the Lausanne Stroke Registry

Details

Serval ID
serval:BIB_E08E72AABDA5
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Cardiac sources of embolism and cerebral infarction--clinical consequences and vascular concomitants: the Lausanne Stroke Registry
Journal
Neurology
Author(s)
Bogousslavsky  J., Cachin  C., Regli  F., Despland  P. A., Van Melle  G., Kappenberger  L.
ISSN
0028-3878 (Print)
Publication state
Published
Issued date
06/1991
Volume
41
Number
6
Pages
855-9
Notes
Comparative Study
Journal Article --- Old month value: Jun
Abstract
We studied clinical characteristics and coexisting causes of stroke in 305 patients admitted to a population-based primary care center with an initial ischemic stroke and a potential cardiac source of embolism (PCSE). Using systematic standardized cardiac, arterial, and cerebral investigations and the logistics of the prospective Lausanne Stroke Registry, we found that nonprogressive onset, hemianopia without hemiparesis or hemisensory disturbances, Wernicke's aphasia, ideomotor apraxia, involvement of specific territories (posterior division of middle cerebral artery, anterior cerebral artery, cerebellum, multiple territories), and a hemorrhagic component were associated with the presence of a PCSE, as compared with 1,006 initial ischemic stroke patients without PCSE. Although age and sex did not differ, the frequency of hypertension, diabetes, cigarette smoking, elevated blood cholesterol, and deep hemispheric or brainstem infarcts was higher in the patients without a PCSE. Nearly one-fourth of the patients with a PCSE had a coexisting potential arterial cause of stroke (large artery greater than or equal to 50% stenosis or small-vessel disease). In the majority of patients with a PCSE (76.7%), cardioembolism was the most likely cause of stroke, although a direct source of embolism was uncommon (4.3%) and intracranial embolic occlusions were present in less than one-half of the patients who were angiographed.
Keywords
Adolescent Adult Aged Aged, 80 and over Cerebral Infarction/*complications Cerebrovascular Disorders/*etiology Female Heart Diseases/*complications Humans Intracranial Embolism and Thrombosis/*complications Male Middle Aged
Pubmed
Web of science
Create date
15/02/2008 11:28
Last modification date
20/08/2019 16:04
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