Practical management of C3 glomerulopathy and Ig-mediated MPGN: facts and uncertainties.
Details
Serval ID
serval:BIB_E003289D80CB
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Practical management of C3 glomerulopathy and Ig-mediated MPGN: facts and uncertainties.
Journal
Kidney international
ISSN
1523-1755 (Electronic)
ISSN-L
0085-2538
Publication state
Published
Issued date
11/2020
Peer-reviewed
Oui
Volume
98
Number
5
Pages
1135-1148
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Publication Status: ppublish
Abstract
In recent years, a substantial body of experimental and clinical work has been devoted to C3 glomerulopathy and Ig-mediated membranoproliferative glomerulonephritis. Despite the rapid accumulation of data, several uncertainties about these 2 rare forms of nephropathies persist. They concern their pathophysiology, classification, clinical course, relevance of biomarkers and of pathology findings, and assessment of the efficacy of the available therapies. The present review discusses the impact of these uncertainties on the clinical management of patients.
Keywords
Complement C3, Glomerulonephritis, Membranoproliferative/drug therapy, Humans, Kidney Diseases/therapy, C3 glomerulopathy, Ig-mediated membranoproliferative glomerulonephritis, complement
Pubmed
Web of science
Open Access
Yes
Create date
08/07/2020 12:47
Last modification date
14/03/2023 7:50