Ultrahigh-field imaging (7 Tesla) in DNET: Unmasking microstructural imaging characteristics - A case report.
Details
Serval ID
serval:BIB_DFEF9B7F565E
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Ultrahigh-field imaging (7 Tesla) in DNET: Unmasking microstructural imaging characteristics - A case report.
Journal
Epilepsy & behavior reports
ISSN
2589-9864 (Electronic)
ISSN-L
2589-9864
Publication state
Published
Issued date
03/2025
Peer-reviewed
Oui
Volume
29
Pages
100749
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Abstract
Commercial ultrahigh-field 7 Tesla (T) MRI has been approved for clinical brain imaging, including applications in epilepsy and brain tumors. Increasing magnetic field strength offers significant advantages over lower-field MRI due to improved spatial resolution, signal-to-noise ratio, and contrast-to-noise ratio. These improvements provide better anatomical delineation and gray-white matter tissue-contrast differentiation. We present a case of a presumed dysembryoplastic neuroepithelial tumor (DNET) imaged at 7 T MRI of the second generation, which revealed an unprecedented level of detail of the complex and intricate tumor architecture. Insights of its different components correlate closely with its known histopathological features. These tumors are unique among low-grade neoplasms due to their distinct clinical presentation, imaging features, and histopathological architecture. DNETs are rare, typically occurring in young patients with refractory epilepsy, and are classified by their well-defined histological subtypes. We review the various MRI patterns of DNET, which have been shown to correlate with histological subtypes and the extent of the epileptogenic zone. Complete tumor resection is essential for long-term control and recurrence prevention, emphasizing the importance of precise preoperative visualization of the tumor and its surrounding tissue. In this case, 7 T images demonstrated superior lesion conspicuity and clearer boundaries, highlighting the advantages of ultrahigh-field MRI in defining the full extent of the lesion. Although 7 T MRI is not yet widely available, it has started to gain an important role in the management of epilepsy, particularly for cases requiring detailed structural analysis.
Keywords
7T MRI, Drug-resistant epilepsy, Dysembryoplastic neuroepithelial tumor, Focal cortical dysplasia, Satellite lesion
Pubmed
Open Access
Yes
Create date
03/03/2025 16:37
Last modification date
04/03/2025 7:59