First experience with Oasis Collagen SOFT SHIELD<sup>®</sup> for epithelial defect after corneal cross-linking.

Details

Serval ID
serval:BIB_DF82CB7234B0
Type
Article: article from journal or magazin.
Publication sub-type
Letter (letter): Communication to the publisher.
Collection
Publications
Institution
Title
First experience with Oasis Collagen SOFT SHIELD<sup>®</sup> for epithelial defect after corneal cross-linking.
Journal
International ophthalmology
Author(s)
Guber I., Bergin C., Malde S., Guber J., Hamada S., Lake D.
ISSN
1573-2630 (Electronic)
ISSN-L
0165-5701
Publication state
Published
Issued date
10/2019
Peer-reviewed
Oui
Volume
39
Number
10
Pages
2149-2151
Language
english
Notes
Publication types: Letter
Publication Status: ppublish
Abstract
To investigate response of dissolving collagen contact lenses as an alternative for bandage contact lenses, for the post-interventional care of epithelial defects after corneal cross-linking (CXL) treatment for keratoconus.
Follow-up visits were performed at day 1, 4 and 1 month after the intervention. We reviewed notes for re-epithelialization, comfort/pain and any untoward effects of Collagen SOFT SHIELD <sup>®</sup> . Assessment included visual acuity (VA), refraction (SE); corneal haze, epithelial erosion and pain status were assessed subjectively on a 4-point scale, from 0 (none) to 3 (severe).
Thirty consecutive CXL patients with collagen shield application after CXL were included. Mean age was 28 years (range from 16 to 51 years old). Pre-CXL VA was 0.7 logMAR IQR 0.4-1.0; post-CXL VA at day 4 and month 1 was 0.6 logMAR IQR 0.4-0.9. Post-operative mean SE was 5.5D ± 4.1D. In all patients, the Collagen SOFT SHIELD <sup>®</sup> was completely dissolved at the 4-day follow-up visit. In most cases, epithelial defect was closed at day 4, on average 0.8 ± 0.5 days post-intervention; all epithelial defects were closed by month 1. Haze was minimal (mean haze score 1.4 ± 0.7 at day 4 and 1.0 ± 0.6 at 1 month). No adverse effects such as infection were observed.
This study indicates that Oasis Collagen SOFT SHIELD <sup>®</sup> is valuable and safe alternative to standard bandage contact lens for the treatment of epithelial defects. This outcome may be of particular interest in patients where the contact lens removal is likely to be problematic.
Keywords
Adolescent, Adult, Collagen/therapeutic use, Contact Lenses, Hydrophilic, Cross-Linking Reagents/therapeutic use, Female, Humans, Keratoconus/therapy, Male, Middle Aged, Photochemotherapy/methods, Photosensitizing Agents/therapeutic use, Visual Acuity, Young Adult, Bandage contact lens, Collagen soft shield, Corneal collagen cross-linking, Corneal epithelial defect, Corneal re-epithelialization
Pubmed
Web of science
Create date
18/02/2019 12:55
Last modification date
24/01/2020 7:19
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