ROS-mediated lipid peroxidation and RES-activated signaling.

Details

Serval ID
serval:BIB_DE696A120100
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
ROS-mediated lipid peroxidation and RES-activated signaling.
Journal
Annual Review of Plant Biology
Author(s)
Farmer E.E., Mueller M.J.
ISSN
1545-2123 (Electronic)
ISSN-L
1543-5008
Publication state
Published
Issued date
2013
Volume
64
Pages
429-450
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Abstract
Nonenzymatic lipid oxidation is usually viewed as deleterious. But if this is the case, then why does it occur so frequently in cells? Here we review the mechanisms of membrane peroxidation and examine the genesis of reactive electrophile species (RES). Recent evidence suggests that during stress, both lipid peroxidation and RES generation can benefit cells. New results from genetic approaches support a model in which entire membranes can act as supramolecular sinks for singlet oxygen, the predominant reactive oxygen species (ROS) in plastids. RES reprogram gene expression through a class II TGA transcription factor module as well as other, unknown signaling pathways. We propose a framework to explain how RES signaling promotes cell "REScue" by stimulating the expression of genes encoding detoxification functions, cell cycle regulators, and chaperones. The majority of the known biological activities of oxygenated lipids (oxylipins) in plants are mediated either by jasmonate perception or through RES signaling networks.
Keywords
Cell Membrane/chemistry, Cell Membrane/metabolism, Lipid Peroxidation, Oxidation-Reduction, Plants/chemistry, Plants/genetics, Reactive Oxygen Species/metabolism, Signal Transduction, Transcription Factors/metabolism
Pubmed
Web of science
Create date
06/10/2016 15:54
Last modification date
15/07/2020 6:26
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