Maternal outcomes and risk factors for COVID-19 severity among pregnant women.

Details

Serval ID
serval:BIB_DDC4714F7413
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Maternal outcomes and risk factors for COVID-19 severity among pregnant women.
Journal
Scientific reports
Author(s)
Vouga M., Favre G., Martinez-Perez O., Pomar L., Acebal L.F., Abascal-Saiz A., Hernandez MRV, Hcini N., Lambert V., Carles G., Sichitiu J., Salomon L., Stirnemann J., Ville Y., de Tejada B.M., Goncé A., Hawkins-Villarreal A., Castillo K., Solsona E.G., Trigo L., Cleary B., Geary M., Bartels H., Al-Kharouf F., Malone F., Higgins M., Keating N., Knowles S., Poncelet C., Ribeiro-do-Valle C.C., Surita F., Dantas-Silva A., Borrelli C., Luz A.G., Fuenzalida J., Carvajal J., Canales M.G., Hernandez O., Grechukhina O., Ko A.I., Reddy U., Figueiredo R., Moucho M., Pinto P.V., De Luca C., De Santis M., de Campos D.A., Martins I., Garabedian C., Subtil D., Bohrer B., Da Rocha Oppermann M.L., Wender MCO, Schuler-Faccini L., Sanseverino MTV, Giugliani C., Friedrich L., Scherer M.H., Mottet N., Ducarme G., Pelerin H., Moreau C., Breton B., Quibel T., Rozenberg P., Giannoni E., Granado C., Monod C., Mueller D., Hoesli I., Bassler D., Heldstab S., Kölble N.O., Sentilhes L., Charvet M., Deprest J., Richter J., Van der Veeken L., Eggel-Hort B., Plantefeve G., Derouich M., Calvache AJN, Lopez-Giron M.C., Burgos-Luna J.M., Escobar-Vidarte M.F., Hecher K., Tallarek A.C., Hadar E., Haratz K.K., Amikam U., Malinger G., Maymon R., Yogev Y., Schäffer L., Toussaint A., Rossier M.C., De Sa RAM, Grawe C., Aebi-Popp K., Radan A.P., Raio L., Surbek D., Böckenhoff P., Strizek B., Kaufmann M., Bloch A., Boulvain M., Johann S., Heldstab S.A., Bernasconi M.T., Grant G., Feki A., Brochut A.M., Giral M., Sedille L., Papadia A., Brugger R.C., Weber B., Fischer T., Kahlert C., Saines K.N., Cambou M., Kanellos P., Chen X., Yin M., Haessig A., Ackermann S., Baud D., Panchaud A.
ISSN
2045-2322 (Electronic)
ISSN-L
2045-2322
Publication state
Published
Issued date
06/07/2021
Peer-reviewed
Oui
Volume
11
Number
1
Pages
13898
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Pregnant women may be at higher risk of severe complications associated with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which may lead to obstetrical complications. We performed a case control study comparing pregnant women with severe coronavirus disease 19 (cases) to pregnant women with a milder form (controls) enrolled in the COVI-Preg international registry cohort between March 24 and July 26, 2020. Risk factors for severity, obstetrical and immediate neonatal outcomes were assessed. A total of 926 pregnant women with a positive test for SARS-CoV-2 were included, among which 92 (9.9%) presented with severe COVID-19 disease. Risk factors for severe maternal outcomes were pulmonary comorbidities [aOR 4.3, 95% CI 1.9-9.5], hypertensive disorders [aOR 2.7, 95% CI 1.0-7.0] and diabetes [aOR2.2, 95% CI 1.1-4.5]. Pregnant women with severe maternal outcomes were at higher risk of caesarean section [70.7% (n = 53/75)], preterm delivery [62.7% (n = 32/51)] and newborns requiring admission to the neonatal intensive care unit [41.3% (n = 31/75)]. In this study, several risk factors for developing severe complications of SARS-CoV-2 infection among pregnant women were identified including pulmonary comorbidities, hypertensive disorders and diabetes. Obstetrical and neonatal outcomes appear to be influenced by the severity of maternal disease.
Keywords
Adult, COVID-19/virology, Case-Control Studies, Female, Humans, Pregnancy, Pregnancy Complications, Infectious/virology, Pregnancy Outcome, Pregnant Women, Premature Birth/virology, Risk Factors, SARS-CoV-2/pathogenicity
Pubmed
Web of science
Open Access
Yes
Create date
12/07/2021 8:54
Last modification date
25/02/2022 7:37
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