Hair follicle stem cells

Details

Serval ID
serval:BIB_DD94496EFD51
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Hair follicle stem cells
Journal
Journal of Investigative Dermatology. Symposium Proceedings
Author(s)
Lavker  R. M., Sun  T. T., Oshima  H., Barrandon  Y., Akiyama  M., Ferraris  C., Chevalier  G., Favier  B., Jahoda  C. A., Dhouailly  D., Panteleyev  A. A., Christiano  A. M.
ISSN
1087-0024 (Print)
Publication state
Published
Issued date
06/2003
Volume
8
Number
1
Pages
28-38
Notes
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review --- Old month value: Jun
Abstract
The workshop on Hair Follicle Stem Cells brought together investigators who have used a variety of approaches to try to understand the biology of follicular epithelial stem cells, and the role that these cells play in regulating the hair cycle. One of the main concepts to emerge from this workshop is that follicular epithelial stem cells are multipotent, capable of giving rise not only to all the cell types of the hair, but also to the epidermis and the sebaceous gland. Furthermore, such multipotent stem cells may represent the ultimate epidermal stem cell. Another example of epithelial stem cell and transit amplifying cell plasticity, was the demonstration that adult corneal epithelium, under the influence of embryonic skin dermis could form an epidermis as well as hair follicles. With regards to the location of follicular epithelial stem cells, immunohistochemical and ultrastructural data was presented, indicating that cells with stem cell attributes were localized to the prominent bulge region of developing human fetal hair follicles. Finally, a new notion was put forth concerning the roles that the bulge-located stem cells and the hair germ cells played with respect to the hair cycle.
Keywords
Animals Embryo/physiology Epidermis/embryology/physiology Epithelium, Corneal/cytology/physiology Hair Follicle/cytology/embryology/growth & development/*physiology Humans Models, Biological Skin/growth & development Stem Cells/*physiology
Pubmed
Web of science
Open Access
Yes
Create date
28/01/2008 8:41
Last modification date
20/08/2019 16:02
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