Zika Virus Infection during Pregnancy and Effects on Early Childhood Development, French Polynesia, 2013-2016.

Details

Serval ID
serval:BIB_DA092EE30C98
Type
Article: article from journal or magazin.
Collection
Publications
Title
Zika Virus Infection during Pregnancy and Effects on Early Childhood Development, French Polynesia, 2013-2016.
Journal
Emerging infectious diseases
Author(s)
Subissi L., Dub T., Besnard M., Mariteragi-Helle T., Nhan T., Lutringer-Magnin D., Barboza P., Gurry C., Brindel P., Nilles E.J., Baud D., Merianos A., Musso D., Glynn J.R., Dupuis G., Cao-Lormeau V.M., Giard M., Mallet H.P.
ISSN
1080-6059 (Electronic)
ISSN-L
1080-6040
Publication state
Published
Issued date
10/2018
Peer-reviewed
Oui
Volume
24
Number
10
Pages
1850-1858
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Congenital Zika virus syndrome consists of a large spectrum of neurologic abnormalities seen in infants infected with Zika virus in utero. However, little is known about the effects of Zika virus intrauterine infection on the neurocognitive development of children born without birth defects. Using a case-control study design, we investigated the temporal association of a cluster of congenital defects with Zika virus infection. In a nested study, we also assessed the early childhood development of children recruited in the initial study as controls who were born without known birth defects,. We found evidence for an association of congenital defects with both maternal Zika virus seropositivity (time of infection unknown) and symptomatic Zika virus infection during pregnancy. Although the early childhood development assessment found no excess burden of developmental delay associated with maternal Zika virus infection, larger, longer-term studies are needed.
Keywords
French Polynesia, Pacific Islands, Zika virus infection, child health, congenital Zika syndrome, early childhood development, viruses
Pubmed
Web of science
Open Access
Yes
Create date
08/10/2018 17:25
Last modification date
20/08/2019 16:59
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