Lambert-Eaton myasthenic syndrome revealing an abdominal neuroblastoma.

Details

Serval ID
serval:BIB_D969703A93BA
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Lambert-Eaton myasthenic syndrome revealing an abdominal neuroblastoma.
Journal
Journal of Pediatric Surgery
Author(s)
de Buys Roessingh A.S., Loriot M.H., Wiesenauer C., Lallier M.
ISSN
1531-5037[electronic]
Publication state
Published
Issued date
2009
Volume
44
Number
8
Pages
E5-7
Language
english
Notes
Publication types: Case Reports ; Journal Article
Abstract
Lambert-Eaton myasthenic syndrome is a paraneoplastic syndrome that may reveal a primitive tumor. Neuroblastoma in children and small cell lung carcinoma in adults are the leading tumors revealed or expressed by paraneoplastic phenomena. The clinical neurologic manifestations of Lambert-Eaton myasthenic syndrome are muscular weakness, sleepiness, absence of reflexes, and dysautonomia. Neurologic manifestations are explained by the induction of an autoimmune response because of the presence of antigens that are expressed by the tumor. Neurologic paraneoplastic disorders may also be the result of toxicity of drugs, coagulopathy, infection, or metabolic diseases. We describe the case of a 13-month-old child with unusual neurologic symptoms because of the presence of an abdominal neuroblastoma.
Keywords
Abdominal Neoplasms/diagnosis, Abdominal Neoplasms/surgery, Diagnosis, Differential, Diagnostic Imaging, Female, Humans, Infant, Lambert-Eaton Myasthenic Syndrome/diagnosis, Lambert-Eaton Myasthenic Syndrome/surgery, Neuroblastoma/diagnosis, Neuroblastoma/surgery
Pubmed
Create date
09/02/2010 14:55
Last modification date
20/08/2019 15:58
Usage data