ISCHEMIC CENTRAL RETINAL VEIN OCCLUSION IN THE ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR ERA.

Details

Serval ID
serval:BIB_D89753885DD0
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
ISCHEMIC CENTRAL RETINAL VEIN OCCLUSION IN THE ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR ERA.
Journal
Retina
Author(s)
Tam E.K., Golchet P., Yung M., DeCroos F.C., Spirn M., Lehmann-Clarke L., Ambresin A., Tsui I.
ISSN
1539-2864 (Electronic)
ISSN-L
0275-004X
Publication state
Published
Issued date
02/2018
Peer-reviewed
Oui
Volume
38
Number
2
Pages
292-298
Language
english
Notes
Publication types: Journal Article ; Multicenter Study
Publication Status: ppublish
Abstract
Anti-vascular endothelial growth factor therapy has improved the prognosis for patients with central retinal vein occlusion (CRVO). However, most studies published to date exclude ischemic CRVO. The purpose of this study was to describe the outcome in eyes with ischemic CRVO treated with anti-vascular endothelial growth factor therapy.
Thirty-seven patients with ischemic CRVO from 3 centers were followed for at least 6 months. Data on patient demographic, vision status, and anti-vascular endothelial growth factor treatments were collected.
Average number of injections during the study period was 5. Younger age was associated with improved vision (P = 0.006). Patients with improved visual outcomes tended to have macular edema as the primary indication for treatment, whereas patients with worse outcomes tended to have neovascularization as the primary indication for treatment.
This study highlights significant variability in the use of anti-vascular endothelial growth factor therapy for ischemic CRVO and underscores that eyes with neovascularization tend to have worse visual outcomes.
Keywords
Aged, Angiogenesis Inhibitors/administration & dosage, Bevacizumab/administration & dosage, Female, Follow-Up Studies, Humans, Incidence, Intravitreal Injections, Ischemia/diagnosis, Ischemia/epidemiology, Ischemia/etiology, Male, Ranibizumab/administration & dosage, Retinal Vein Occlusion/complications, Retinal Vein Occlusion/diagnosis, Retinal Vein Occlusion/drug therapy, Retrospective Studies, Tomography, Optical Coherence, United States/epidemiology, Vascular Endothelial Growth Factor A/antagonists & inhibitors, Visual Acuity
Pubmed
Web of science
Create date
28/02/2017 19:55
Last modification date
20/08/2019 15:58
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