Early improvement in left ventricular diastolic function after relief of chronic right ventricular pressure overload

Details

Serval ID
serval:BIB_D7C2401F8043
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Early improvement in left ventricular diastolic function after relief of chronic right ventricular pressure overload
Journal
Circulation
Author(s)
Dittrich  H. C., Chow  L. C., Nicod  P. H.
ISSN
0009-7322 (Print)
Publication state
Published
Issued date
10/1989
Volume
80
Number
4
Pages
823-30
Notes
Journal Article --- Old month value: Oct
Abstract
Chronic right ventricular pressure overload is associated with left ventricular diastolic dysfunction. Whether or not an abrupt reduction in pulmonary artery pressure in patients with chronic pulmonary hypertension results in early improvement of left ventricular diastolic function is unknown. To assess this, the Doppler indexes of left ventricular diastolic function and echocardiographic measures of left ventricular volume were analyzed in 22 patients (age, 41 +/- 14 years, mean +/- SD) before and within 1 week after pulmonary thromboendarterectomy for chronic thromboembolic pulmonary hypertension. Mean duration of cardiopulmonary symptoms was 37 months (range, 4 months to 9 years). After operation, mean pulmonary artery pressure and pulmonary vascular resistance decreased (50 +/- 13 to 29 +/- 9 mm Hg and 904 +/- 654 to 283 +/- 243 dynes.sec/cm5, respectively, both p less than 0.001), pulmonary artery wedge pressure was unchanged (11 +/- 5 to 12 +/- 5 mm Hg), and cardiac index increased (2.0 +/- 0.5 to 2.8 +/- 0.7 l/min/m2 p less than 0.001). Left ventricular end-diastolic volume and stroke volume increased significantly (58.5 +/- 18.0 to 76.6 +/- 25.0 ml and 30.3 +/- 12.3 to 41.8 +/- 12.5 ml, respectively, both p less than 0.001) after surgery.(ABSTRACT TRUNCATED AT 250 WORDS)
Keywords
Adult Aged Chronic Disease Diastole Echocardiography Echocardiography, Doppler *Endarterectomy Female Heart/*physiopathology Heart Catheterization Heart Ventricles Humans Hypertension, Pulmonary/etiology/*surgery Male Middle Aged Postoperative Period Pulmonary Embolism/complications/physiopathology/*surgery
Pubmed
Web of science
Create date
25/01/2008 13:59
Last modification date
20/08/2019 15:57
Usage data