Health-related quality of life in patients with narcolepsy types 1 and 2 from a Sleep Center in Brazil.

Details

Ressource 1Request a copy Sous embargo indéterminé.
State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_D60CBDD9F27D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Health-related quality of life in patients with narcolepsy types 1 and 2 from a Sleep Center in Brazil.
Journal
Arquivos de neuro-psiquiatria
Author(s)
Cremaschi R.C., Hirotsu C., Tufik S., Coelho F.M.
ISSN
1678-4227 (Electronic)
ISSN-L
0004-282X
Publication state
Published
Issued date
29/06/2020
Peer-reviewed
Oui
Volume
78
Number
8
Pages
488-493
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Narcolepsy patients have higher prevalence of comorbidities, such as obesity, depression, and pain. Narcolepsy symptoms and concomitant medical conditions can impact the daily activities of patients. The objective of this study is to describe the quality of life in a sample of patients with narcolepsy, and the influence of the nutritional status in health domains.
At Unifesp, two groups of 33 patients (narcolepsy types 1 and 2 meeting 2014 criteria, concerning hypocretin-1) and 33 controls without sleepiness, matched by age and sex, filled out the SF-36.
Narcolepsy groups, regardless of their nutritional status, had significantly lower scores in all domains, compared to controls, mainly in Role-physical, Role-emotional, and Energy/Fatigue. Role-physical score was lower in type 1 than in type 2 and controls (37.8±1.0 vs. 50.0±1.2 vs. 85.6±1.6; p<0.0001). Obese with type 2 narcolepsy scored lower than type 1 in physical scales.
In a Sleep Center in São Paulo, Brazil, physical and mental health were impaired in narcolepsy types 1 and 2. The first report of the poor health status in Brazilians with narcolepsy type 2 suggests that obesity negatively affects physical domains.
Pubmed
Web of science
Open Access
Yes
Create date
08/07/2020 11:31
Last modification date
14/10/2020 5:23
Usage data