Creation of a predictive calculator to determine adequacy of occlusion of the woven endobridge (WEB) device in intracranial aneurysms-A retrospective analysis of the WorldWide WEB Consortium database.

Musmar, B.; Adeeb, N.; Gendreau, J.; Horowitz, M.A.; Salim, H.A.; Sanmugananthan, P.; Aslan, A.; Brown, N.J.; Cancelliere, N.M.; McLellan, R.M.; Algin, O.; Ghozy, S.; Dibas, M.; Orscelik, A.; Senol, Y.C.; Lay, S.V.; Guenego, A.; Renieri, L.; Carnevale, J.; Saliou, G.; Mastorakos, P.; El Naamani, K.; Shotar, E.; Premat, K.; Möhlenbruch, M.; Kral, M.; Doron, O.; Chung, C.; Salem, M.M.; Lylyk, I.; Foreman, P.M.; Vachhani, J.A.; Shaikh, H.; Župančić, V.; Hafeez, M.U.; Catapano, J.; Waqas, M.; Tutino, V.M.; Gokhan, Y.; Imamoglu, C.; Bayrak, A.; Rabinov, J.D.; Ren, Y.; Schirmer, C.M.; Piano, M.; Kühn, A.L.; Michelozzi, C.; Elens, S.; Starke, R.M.; Hassan, A.E.; Ogilvie, M.; Nguyen, A.; Jones, J.; Brinjikji, W.; Nawka, M.T.; Psychogios, M.; Ulfert, C.; Bengzon Diestro, J.D.; Pukenas, B.; Burkhardt, J.K.; Huynh, T.; Martinez-Gutierrez, J.C.; Essibayi, M.A.; Sheth, S.A.; Spiegel, G.; Tawk, R.; Lubicz, B.; Panni, P.; Puri, A.S.; Pero, G.; Nossek, E.; Raz, E.; Killer-Oberfalzer, M.; Griessenauer, C.J.; Asadi, H.; Siddiqui, A.; Brook, A.L.; Altschul, D.; Ducruet, A.F.; Albuquerque, F.C.; Regenhardt, R.W.; Stapleton, C.J.; Kan, P.; Kalousek, V.; Lylyk, P.; Boddu, S.; Knopman, J.; Aziz-Sultan, M.A.; Tjoumakaris, S.I.; Clarençon, F.; Limbucci, N.; Bydon, M.; Hasan, D.; Cuellar-Saenz, H.H.; Jabbour, P.M.; Pereira, V.M.; Patel, A.B.; Dmytriw, A.A.

doi:10.1177/15910199241267320

Creation of a predictive calculator to determine adequacy of occlusion of the woven endobridge (WEB) device in intracranial aneurysms-A retrospective analysis of the WorldWide WEB Consortium database.

Details

Request a copy

Serval ID

serval:BIB_D5B42A447F41

Type

Article: article from journal or magazin.

Collection

Publications

Institution

UNIL/CHUV

Title

Creation of a predictive calculator to determine adequacy of occlusion of the woven endobridge (WEB) device in intracranial aneurysms-A retrospective analysis of the WorldWide WEB Consortium database.

Journal

Interventional neuroradiology

Author(s)

Musmar B., Adeeb N., Gendreau J., Horowitz M.A., Salim H.A., Sanmugananthan P., Aslan A., Brown N.J., Cancelliere N.M., McLellan R.M., Algin O., Ghozy S., Dibas M., Orscelik A., Senol Y.C., Lay S.V., Guenego A., Renieri L., Carnevale J., Saliou G., Mastorakos P., El Naamani K., Shotar E., Premat K., Möhlenbruch M., Kral M., Doron O., Chung C., Salem M.M., Lylyk I., Foreman P.M., Vachhani J.A., Shaikh H., Župančić V., Hafeez M.U., Catapano J., Waqas M., Tutino V.M., Gokhan Y., Imamoglu C., Bayrak A., Rabinov J.D., Ren Y., Schirmer C.M., Piano M., Kühn A.L., Michelozzi C., Elens S., Starke R.M., Hassan A.E., Ogilvie M., Nguyen A., Jones J., Brinjikji W., Nawka M.T., Psychogios M., Ulfert C., Bengzon Diestro J.D., Pukenas B., Burkhardt J.K., Huynh T., Martinez-Gutierrez J.C., Essibayi M.A., Sheth S.A., Spiegel G., Tawk R., Lubicz B., Panni P., Puri A.S., Pero G., Nossek E., Raz E., Killer-Oberfalzer M., Griessenauer C.J., Asadi H., Siddiqui A., Brook A.L., Altschul D., Ducruet A.F., Albuquerque F.C., Regenhardt R.W., Stapleton C.J., Kan P., Kalousek V., Lylyk P., Boddu S., Knopman J., Aziz-Sultan M.A., Tjoumakaris S.I., Clarençon F., Limbucci N., Bydon M., Hasan D., Cuellar-Saenz H.H., Jabbour P.M., Pereira V.M., Patel A.B., Dmytriw A.A.

ISSN

2385-2011 (Electronic)

ISSN-L

1591-0199

Publication state

In Press

Peer-reviewed

Oui

Language

english

Notes

Publication types: Journal Article
Publication Status: aheadofprint

Abstract

Endovascular treatment with the woven endobridge (WEB) device has been widely utilized for managing intracranial aneurysms. However, predicting the probability of achieving adequate occlusion (Raymond-Roy classification 1 or 2) remains challenging.
Our study sought to develop and validate a predictive calculator for adequate occlusion using the WEB device via data from a large multi-institutional retrospective cohort.
We used data from the WorldWide WEB Consortium, encompassing 356 patients from 30 centers across North America, South America, and Europe. Bivariate and multivariate regression analyses were performed on a variety of demographic and clinical factors, from which predictive factors were selected. Calibration and validation were conducted, with variance inflation factor (VIF) parameters checked for collinearity.
A total of 356 patients were included: 124 (34.8%) were male, 108 (30.3%) were elderly (≥65 years), and 118 (33.1%) were current smokers. Mean maximum aneurysm diameter was 7.09 mm (SD 2.71), with 112 (31.5%) having a daughter sac. In the multivariate regression, increasing aneurysm neck size (OR 0.706 [95% CI: 0.535-0.929], p = 0.13) and partial aneurysm thrombosis (OR 0.135 [95% CI: 0.024-0.681], p = 0.016) were found to be the only statistically significant variables associated with poorer likelihood of achieving occlusion. The predictive calculator shows a c-statistic of 0.744. Hosmer-Lemeshow goodness-of-fit test indicated a satisfactory model fit with a p-value of 0.431. The calculator is available at: https://neurodx.shinyapps.io/WEBDEVICE/.
The predictive calculator offers a substantial contribution to the clinical toolkit for estimating the likelihood of adequate intracranial aneurysm occlusion by WEB device embolization.

Keywords

Aneurysm, WEB device, cerebrovascular, prediction

OAI-PMH

oai:serval.unil.ch:BIB_D5B42A447F41

DOI

10.1177/15910199241267320

Pubmed

39127463

Web of science

001334813700001

Create date

19/08/2024 7:57