Pitfalls in aminoacid and organic acid analysis: 3-hydroxypropionic aciduria.

Details

Serval ID
serval:BIB_D49142735C0E
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Pitfalls in aminoacid and organic acid analysis: 3-hydroxypropionic aciduria.
Journal
European journal of pediatrics
Author(s)
Bachmann C., Boulat O., Meyrat B.J., Colombo J.P., Pilloud P.
ISSN
0340-6199
Publication state
Published
Issued date
1994
Peer-reviewed
Oui
Volume
153
Number
7 Suppl 1
Pages
S23-6
Language
english
Notes
Publication types: Case Reports ; Journal Article - Publication Status: ppublish
Abstract
Pitfalls in organic acid analysis can originate from inadequate methodology, analytical interferences, in vivo interactions and from pre-analytical conditions which often are unknown to the specialized analytical laboratory. Among the latter, ingested food and additives, metabolites of food processing or medications have to be considered. Bacterial metabolites from the gastrointestinal or urogenital system or formed after sample collection can lead to pitfalls as well. An example of such a patient whose urinary metabolites mimic at first glance inherited propionic aciduria is described.
Keywords
Amino Acid Metabolism, Inborn Errors, Diagnosis, Differential, Humans, Infant, Newborn, Lactates, Lactic Acid, Male, Specimen Handling
Pubmed
Web of science
Create date
28/01/2008 9:09
Last modification date
20/08/2019 15:54
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