Demographic and clinical predictors of leptomeningeal collaterals in stroke patients.

Details

Serval ID
serval:BIB_D417A9C1F347
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Demographic and clinical predictors of leptomeningeal collaterals in stroke patients.
Journal
Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Author(s)
Malik N., Hou Q., Vagal A., Patrie J., Xin W., Michel P., Eskandari A., Jovin T., Wintermark M.
ISSN
1532-8511 (Electronic)
ISSN-L
1052-3057
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
23
Number
8
Pages
2018-2022
Language
english
Notes
Publication types: Journal Article Publication Status: ppublish
Abstract
BACKGROUND: Leptomeningeal collaterals improve outcome after stroke, including reduction of hemorrhagic complications after thrombolytic or endovascular therapy, smaller infarct size, and reduction in symptoms at follow-up evaluation. The purpose of this study was to determine the demographic and clinical variables that are associated with a greater degree of cerebral collaterals.
METHODS: Clinical data of patients presenting with M1 occlusions of the middle cerebral artery (MCA) and associated computed tomography angiography studies after admission from 3 separate institutions were retrospectively compiled (n = 82). Occluded hemispheres were evaluated against the intact hemisphere for degree of collateralization in the MCA territory. Regression analysis of variance was conducted between clinical variables and collateral score to determine which variables associate with greater collateral development.
RESULTS: Smaller infarct size corresponded to greater collateral scores, whereas older age and statin use corresponded to lower collateral scores (P < .001).
CONCLUSIONS: Cerebral collateralization is influenced by age and statin use and influences infarct size.
Pubmed
Web of science
Create date
09/10/2014 16:46
Last modification date
20/08/2019 15:54
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