Evidence for Parachlamydia in bovine abortion.

Details

Serval ID
serval:BIB_D3D4D1717296
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Evidence for Parachlamydia in bovine abortion.
Journal
Veterinary Microbiology
Author(s)
Ruhl S., Casson N., Kaiser C., Thoma R., Pospischil A., Greub G., Borel N.
ISSN
0378-1135 (Print)
ISSN-L
0378-1135
Publication state
Published
Issued date
2009
Peer-reviewed
Oui
Volume
135
Number
1-2
Pages
169-174
Language
english
Abstract
Bovine abortion of unknown infectious aetiology still remains a major economic problem. In this study, we focused on a new possible abortigenic agent called Parachlamydia acanthamoebae. Retrospective samples (n=235) taken from late-term abortions in cattle were investigated by real-time diagnostic PCR for Chlamydiaceae and Parachlamydia spp., respectively. Histological sections of cases positive by real-time PCR for any Chlamydia-related agent were further examined by immunohistochemistry using specific antibodies. Chlamydophila abortus was detected only in three cases (1.3%) by real-time PCR and ArrayTube Microarray playing a less important role in bovine abortion compared to the situation in small ruminants in Switzerland. By real-time PCR as many as 43 of 235 (18.3%) cases turned out to be positive for Parachlamydia. The presence of Parachlamydia within placental lesions was confirmed in 35 cases (81.4%) by immunohistochemistry. The main histopathological feature in parachlamydial abortion was purulent to necrotizing placentitis (25/43). Parachlamydia should be considered as a new abortigenic agent in Swiss cattle. Since Parachlamydia may be involved in lower respiratory tract infections in humans, bovine abortion material should be handled with care given the possible zoonotic risk.
Keywords
Abortion, Veterinary/microbiology, Animals, Cattle, Cattle Diseases/microbiology, Chlamydiales/isolation & purification, Female, Gram-Negative Bacterial Infections/microbiology, Gram-Negative Bacterial Infections/veterinary, Placenta Diseases/microbiology, Placenta Diseases/pathology, Pregnancy
Pubmed
Web of science
Create date
03/04/2016 20:02
Last modification date
20/08/2019 15:53
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