Performance of different adiposity measures for predicting cardiovascular risk in adolescents.

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State: Public
Version: Final published version
Serval ID
serval:BIB_D3C69D95C58C
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Performance of different adiposity measures for predicting cardiovascular risk in adolescents.
Journal
Scientific reports
Author(s)
Zhao M., Bovet P., Ma C., Xi B.
ISSN
2045-2322 (Electronic)
ISSN-L
2045-2322
Publication state
Published
Issued date
06/03/2017
Peer-reviewed
Oui
Volume
7
Pages
43686
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: epublish
Abstract
This study aims to compare the performance of body mass index (BMI), waist circumference (WC), and waist-to-height-ratio (WHtR) to predict the presence of at least 3 main CV risk factors in US adolescents. A total of 3621 adolescents (boys: 49.9%) aged 12-17 years from the US National Health and Nutrition Examination Survey (1999-2012) were included in this study. Measured CV risk factors included systolic/diastolic blood pressure, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and fasting plasma glucose. The AUC of BMI-z score, WC-z score and WHtR-z score to predict at least three CV risk factors were similar (~0.85), irrespective of criteria used to define abnormal levels of CV risk factors. A 1-SD increase in any of three indices to predict CV risk was also similar for the three adiposity scores. For instance, a 1-SD increase risk in BMI-z score, WC-z score and WHtR-z score was 3.32 (95%CI 2.53-4.36), 3.43 (95%CI 2.64-4.46), and 3.45 (95%CI 2.64-4.52), respectively, in the total population using the International Diabetes Federation definition. In addition, the most efficient WHtR cut-off for screening CV risk was ~0.50 in US adolescents. In summary, BMI, WC and WHtR performed similarly well to predict the presence of at least 3 main CV risk factors among US adolescents.
Keywords
Adiposity, Adolescent, Age Factors, Area Under Curve, Biomarkers, Body Mass Index, Body Weights and Measures, Cardiovascular Diseases/epidemiology, Cardiovascular Diseases/etiology, Child, Female, Humans, Male, Obesity/complications, Risk Assessment, Risk Factors, United States/epidemiology, Waist Circumference, Waist-Height Ratio, Waist-Hip Ratio
Pubmed
Web of science
Open Access
Yes
Create date
14/03/2017 10:57
Last modification date
20/08/2019 15:53
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