Impact of synthetic elements on aortic root haemodynamics: computed fluid dynamics of aortic root reconstruction and valve reimplantation.

Details

Serval ID
serval:BIB_D38FC75BFB55
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Impact of synthetic elements on aortic root haemodynamics: computed fluid dynamics of aortic root reconstruction and valve reimplantation.
Journal
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
Author(s)
Berdajs D., Mosbahi S., Strano F., Forro Z., Burki M., von Segesser L.K.
ISSN
1873-734X (Electronic)
ISSN-L
1010-7940
Publication state
Published
Issued date
01/04/2017
Peer-reviewed
Oui
Volume
51
Number
3
Pages
432-441
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
The aim was to evaluate the impact of the aortic valve reimplantation (David) and of the aortic root (AoR) remodelling (Yacoub) on the AoR haemodynamics.
In an experimental setup where the clinical scenario of Yacoub, ( n =  5, domestic pig) and of David ( n =  5, domestic pig) procedure was performed in each AoR, six high-fidelity (200 Hz) sonomicrometric crystals were implanted. Crystals were positioned at three commissures with their projection at the root base. In post-measurement processing 3D deformation of both AoR was determined and used for computed fluid dynamic modelling in order to evaluate pressure, velocity and shear stress profiles.
In David AoR: high pressure (> 150 mmHg) and low to moderate shear stress (0-30 Pa) were found from the period of isovolemic contraction to the closure of the aortic valve. At mid diastole pressure augmentation (> 120 mmHg) a low shear stress (0-10 Pa) was registered at the leaflets, three commissures, and intervalvular triangles. In Yacoub AoR: high pressure (110-130 mmHg) with moderate low shear stress (0-30 Pa) was only registered at isovolemic contraction.
The results show that haemodynamic conditions following a David procedure have a less favourable pattern as compared to a Yacoub AoR. In David AoR, high pressure and low shear stress are present during 2/3 of the cardiac cycle, whereas in Yacoub root, these conditions are present only for a short period of isovolemic contraction.

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Web of science
Create date
03/01/2017 19:12
Last modification date
20/08/2019 15:53
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