Pulmonary embolism: specific risk factor after pancreas resection?

Details

Serval ID
serval:BIB_D30CD7F35E34
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Pulmonary embolism: specific risk factor after pancreas resection?
Journal
Pancreas
Author(s)
Kokudo T., Uldry E., Demartines N., Halkic N.
ISSN
1536-4828 (Electronic)
ISSN-L
0885-3177
Publication state
Published
Issued date
2014
Peer-reviewed
Oui
Volume
43
Number
6
Pages
891-894
Language
english
Notes
Publication types: Journal ArticlePublication Status: ppublish
Abstract
OBJECTIVE: Pulmonary embolism (PE) after major abdominal surgery is a serious and potentially lethal complication. The purpose of the present study was to identify risk factors for postoperative PE after pancreas resection.
METHODS: Our prospective database for pancreatic surgery was retrospectively analyzed for patients treated between January 2006 and August 2012 in a tertiary care Swiss hospital. Risk factors for PE were identified in univariate and multivariate analyses that included preoperative, intraoperative, and postoperative variables.
RESULTS: Among 251 patients, 187 underwent pancreato-duodenectomy (PD), 62 underwent distal pancreatectomy, and 2 underwent other types of pancreas resections. PE was diagnosed in 13 patients (7.0%) after PD and none after other procedures. Compared with the non-PE group, the PE group had higher body mass indices (≥25 kg/m, P = 0.04), longer median operation times (P = 0.009), higher rates of severe abdominal complications (P < 0.001), longer median intensive care unit stays (P = 0.003), and longer hospital stays (P = 0.01). Multivariate analyses identified the following independent predictors for PE: a history of thromboembolic events (odds ratio [OR], 22.3), prolonged operation time (OR, 5.76), and major abdominal complications (OR, 10.8).
CONCLUSIONS: Prolonged operation times and major postoperative abdominal complications were strong risk factors for PE after PD, in both univariate and multivariate analyses.
Keywords
Aged, Databases, Factual/statistics & numerical data, Female, Humans, Intensive Care Units/statistics & numerical data, Length of Stay/statistics & numerical data, Logistic Models, Male, Middle Aged, Multivariate Analysis, Pancreatectomy/adverse effects, Pancreatectomy/methods, Postoperative Complications/diagnosis, Postoperative Complications/etiology, Prognosis, Pulmonary Embolism/diagnosis, Pulmonary Embolism/etiology, Retrospective Studies, Risk Factors, Tertiary Care Centers/statistics & numerical data
Pubmed
Web of science
Create date
18/10/2016 16:30
Last modification date
20/08/2019 15:53
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