Fatal hypoxic hepatitis in a patient with hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber's disease).

Details

Serval ID
serval:BIB_D2712C37DB27
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Fatal hypoxic hepatitis in a patient with hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber's disease).
Journal
Acta Gastro-enterologica Belgica
Author(s)
Henrion J., Deltenre P., Peny M.O., Dumoulin P., Laurent Y., Brenard R.
ISSN
0001-5644 (Print)
ISSN-L
0001-5644
Publication state
Published
Issued date
2010
Volume
73
Number
1
Pages
61-64
Language
english
Notes
Publication types: Case Reports ; Journal ArticlePublication Status: ppublish
Abstract
Hypoxic (ischemic) hepatitis generally requires the concurrence of an underlying condition which chronically exposes the liver to some degree of hypoxia (for example, congestive heart failure) combined with a triggering event (for example, arrhythmia) which further decreases the oxygen supply. We report a case of hypoxic hepatitis in which hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber's disease) constituted this underlying condition and gastrointestinal hemorrhage was the triggering event. To our knowledge, this is the first reported case of hypoxic hepatitis in hereditary hemorrhagic telangiectasia with the exception of therapeutic ligation or embolization of the hepatic artery so as to decrease shunting of liver blood. Hemodynamic mechanisms are proposed to explain this particular outcome.
Keywords
Anoxia/diagnosis, Anoxia/etiology, Fatal Outcome, Female, Hepatitis/diagnosis, Hepatitis/etiology, Humans, Ischemia/diagnosis, Ischemia/etiology, Middle Aged, Telangiectasia, Hereditary Hemorrhagic/complications, Telangiectasia, Hereditary Hemorrhagic/pathology
Pubmed
Web of science
Create date
06/12/2013 10:11
Last modification date
20/08/2019 15:52
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