Combined positron emission tomography and magnetic resonance imaging for the planning of stereotactic brain biopsies in children: experience in 9 cases.

Details

Serval ID
serval:BIB_D25C4A90A15B
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Combined positron emission tomography and magnetic resonance imaging for the planning of stereotactic brain biopsies in children: experience in 9 cases.
Journal
Pediatric Neurosurgery
Author(s)
Pirotte B., Goldman S., Salzberg S., Wikler D., David P., Vandesteene A., Van Bogaert P., Salmon I., Brotchi J., Levivier M.
ISSN
1016-2291 (Print)
ISSN-L
1016-2291
Publication state
Published
Issued date
2003
Peer-reviewed
Oui
Volume
38
Number
3
Pages
146-155
Language
english
Notes
Publication types: Journal Article ; Review Publication Status: ppublish
Abstract
Because brain tumors can be histologically heterogeneous, stereotactic brain biopsies (SBB) may lead to inaccurate diagnosis or grading. Positron emission tomography (PET) has been used in pediatric neuro-oncology to help in the understanding and management of brain neoplasms. We combined PET and magnetic resonance (MR) imaging in the planning of SBB in 9 children (5 males and 4 females, aged 2-14 years) with infiltrative, ill-defined brain lesions. Tracers used for PET were (18)F-2-fluoro-2-deoxy-D-glucose in 4 cases, (11)C-methionine in 2 cases and both tracers in 3 cases. Biopsy targets were selected in hypermetabolic areas. PET-guided SBB provided accurate histological diagnosis in all patients and allowed a reduction of the number of trajectories in lesions located in functional areas. It also helped in better understanding and management of complex cases. This preliminary series suggests that combining PET and MR imaging in the planning of SBB in children (1) improves the diagnostic yield of SBB in infiltrative, ill-defined brain lesions, (2) makes it possible to reduce the sampling in high-risk/functional areas and (3) improves the quality of therapeutic management of pediatric brain tumors.
Keywords
Adolescent, Biopsy, Brain Neoplasms/pathology, Brain Neoplasms/radionuclide imaging, Child, Child, Preschool, Female, Granuloma/pathology, Granuloma/radionuclide imaging, Humans, Infant, Magnetic Resonance Imaging, Male, Neoplasms, Neuroepithelial/pathology, Neoplasms, Neuroepithelial/radionuclide imaging, Patient Care Planning, Reproducibility of Results, Stereotaxic Techniques, Tomography, Emission-Computed
Pubmed
Web of science
Create date
20/01/2008 17:35
Last modification date
20/08/2019 15:52
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