Tuberculous colitis mimicking Crohn's disease

Details

Serval ID
serval:BIB_D1E91AC24C9B
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Tuberculous colitis mimicking Crohn's disease
Journal
American Journal of Gastroenterology
Author(s)
Arnold  C., Moradpour  D., Blum  H. E.
ISSN
0002-9270 (Print)
Publication state
Published
Issued date
11/1998
Volume
93
Number
11
Pages
2294-6
Notes
Case Reports
Journal Article --- Old month value: Nov
Abstract
Intestinal tuberculosis is a rare disease in western countries and may mimic a variety of gastrointestinal disorders. Here, we report the case of a 63-yr-old patient who presented with profuse bleeding from a deep rectal ulcer. Similar lesions were found in different parts of the colon. Multilocular colorectal carcinoma was suspected based on the macroscopic appearance. Histology, however, suggested Crohn's disease. Intestinal tuberculosis was initially ruled out by negative staining for acid-fast bacilli, mycobacterial culture, and polymerase chain reaction analysis. A treatment for Crohn's disease was started. Endoscopic reexamination revealed progressive disease with extensive ulcerations of the terminal ileum. Histopathological examination then revealed acid-fast bacilli in the colonic mucosa typical for mycobacterium tuberculosis infection. This case emphasizes the need to include intestinal tuberculosis in the initial differential diagnosis of ulcerative colorectal lesions also in the western population.
Keywords
Colitis/*diagnosis Crohn Disease/*diagnosis Diagnosis, Differential Female Humans Middle Aged Tuberculosis, Gastrointestinal/*diagnosis
Pubmed
Web of science
Create date
25/01/2008 16:05
Last modification date
20/08/2019 15:52
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