How useful is PET/CT imaging in the management of post-transplant lymphoproliferative disease after liver transplantation?
Details
Download: American J Transplantation - 2006 - McCormack - How Useful is PET CT Imaging in the Management of Post‐Transplant.pdf (204.67 [Ko])
State: Public
Version: Final published version
License: Not specified
State: Public
Version: Final published version
License: Not specified
Serval ID
serval:BIB_D0595E7F5518
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
How useful is PET/CT imaging in the management of post-transplant lymphoproliferative disease after liver transplantation?
Journal
American Journal of Transplantation
ISSN
1600-6135 (Print)
ISSN-L
1600-6135
Publication state
Published
Issued date
2006
Peer-reviewed
Oui
Volume
6
Number
7
Pages
1731-1736
Language
english
Notes
Publication types: Case Reports ; Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Abstract
Post-transplant lymphoproliferative disease (PTLD) is a serious and potentially life-threatening complication after solid organ transplantation. Here, we report our first experience with the use of PET/CT (positron emission tomography combined with computed tomogram) for the management of patients with PTLD after liver transplantation. Four patients with histologically proven PTLD were analyzed. Conventional work-up included physical examination and head-to-pelvis CT. PET/CT was used in one patient for initial staging and in all patients for follow-up. PET/CT positive findings underwent biopsy. Information provided by PET/CT resulted in a change of medical management in three of the four patients. Conventional work-up missed residual disease after surgery in one and failed to detect a tumor relapse in another patient. However, one patient disclosed a false positive PET/CT finding in the lungs. In conclusion, PET/CT may be a useful tool for staging and therapy monitoring of PTLD after liver transplantation.
Keywords
Adolescent, Female, Humans, Liver Transplantation/radiography, Liver Transplantation/radionuclide imaging, Lymphoproliferative Disorders/radiography, Lymphoproliferative Disorders/radionuclide imaging, Middle Aged, Positron-Emission Tomography/methods, Tomography, X-Ray Computed/methods
Pubmed
Web of science
Open Access
Yes
Create date
05/08/2012 11:21
Last modification date
10/02/2022 8:27