Dispositifs de délivrance de principes actifs pour des applications ophtalmologiques [Drug delivery systems for intraocular applications].
Details
Serval ID
serval:BIB_D0274BCEA57C
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Dispositifs de délivrance de principes actifs pour des applications ophtalmologiques [Drug delivery systems for intraocular applications].
Journal
Journal Français D'ophtalmologie
ISSN
1773-0597 (Electronic)
ISSN-L
0181-5512
Publication state
Published
Issued date
2007
Peer-reviewed
Oui
Volume
30
Number
10
Pages
1070-1088
Language
french
Notes
Publication types: English Abstract ; Journal Article ; ReviewPublication Status: ppublish
Abstract
Numerous drug delivery systems (DDSs) can be used as intraocular tools to provide a sustained and calibrated release for a specific drug. Great progress has been made on the design, biocompatibility, bioavailability, and efficacy of DDSs. Although several of them are undergoing clinical trials, a few are already on the market and could be of a routine use in clinical practice. Moreover, miniaturization of the implants makes them less and less traumatic for the eye tissues and some DDSs are now able to target certain cells or tissues specifically. An overview of ocular implants with therapeutic application potentials is provided.
Keywords
Animals, Delayed-Action Preparations, Drug Delivery Systems/instrumentation, Drug Implants, Equipment Design, Eye/drug effects, Eye Diseases/drug therapy, Humans, Liposomes, Miniaturization, Nanoparticles, Particle Size, Polymers, Prostheses and Implants, Vitreous Body/drug effects, Vitreous Body/pathology
Pubmed
Web of science
Create date
27/08/2013 11:20
Last modification date
20/08/2019 16:50