Influence of occupational exposure to pigs or chickens on human gut microbiota composition in Thailand.

Details

Ressource 1Download: 2022_Sudatip_Influence_OneHealth_100463.pdf (1389.05 [Ko])
State: Public
Version: Final published version
License: CC BY 4.0
Serval ID
serval:BIB_CFF8FC105406
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Influence of occupational exposure to pigs or chickens on human gut microbiota composition in Thailand.
Journal
One health
Author(s)
Sudatip D., Mostacci N., Thamlikitkul V., Oppliger A., Hilty M.
ISSN
2352-7714 (Print)
ISSN-L
2352-7714
Publication state
Published
Issued date
12/2022
Peer-reviewed
Oui
Volume
15
Pages
100463
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Abstract
Pig farming's influence on human gut microbiota has been observed previously, but its pervasiveness is unclear. We therefore aimed at studying whether pig farming influenced human gut microbiota composition in Thailand and whether poultry farming did too. We collected human stool samples (71 pig farmers, 131 chicken farmers, 55 non-farmers) for 16S rRNA sequencing and performed subsequent DADA2 analyses of amplicon sequence variants. We found that Alpha diversity values were highest among chicken farmers. Relative abundances of Prevotellaceae were significantly higher among pig farmers than among chicken farmers and non-farmers (p < 0.001). Beta diversity plots revealed different clustering according to occupation. The presence or absence of antimicrobial-resistant Escherichia coli was not associated with changes in gut microbiota composition. In conclusion, occupation was the strongest factor influencing gut microbiota composition in Thailand. We hypothesize that Prevotellaceae amplicon sequence variants are transmitted from pigs to pig farmers.
Keywords
Infectious Diseases, Public Health, Environmental and Occupational Health, Allergy, Antimicrobial resistance, Microbial communities, One health, Pig farming, Prevotellaceae
Pubmed
Web of science
Open Access
Yes
Create date
15/12/2022 15:18
Last modification date
13/09/2023 7:15
Usage data