Association between post-traumatic stress disorder and hypertension in Congolese exposed to violence: a case-control study.

Details

Serval ID
serval:BIB_CFF7B80A02EF
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Association between post-traumatic stress disorder and hypertension in Congolese exposed to violence: a case-control study.
Journal
Journal of hypertension
Author(s)
Bapolisi A., Maurage P., Pappaccogli M., Georges CMG, Petit G., Balola M., Cikomola C., Bisimwa G., Burnier M., Persu A., de Timary P.
ISSN
1473-5598 (Electronic)
ISSN-L
0263-6352
Publication state
Published
Issued date
01/04/2022
Peer-reviewed
Oui
Volume
40
Number
4
Pages
685-691
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Numerous risk factors have been involved in the pathogenesis of hypertension. The contribution of psychological factors, including post-traumatic stress disorder, remains largely underexplored, despite their potential role in hypertension.
We compared the prevalence of trauma, post-traumatic stress and other psychological disorders between hypertensive and normotensive patients from Bukavu (Democratic Republic of Congo), a 25-year war-exposed city.
In this case-control study, we assessed past traumatic events with the Stressful-Events-Scale, post-traumatic stress disorder through the post-traumatic diagnostic scale, depression and alcohol use disorder through the MINI-International-Neuropsychiatric-Interview, and emotion regulation through the Emotion-Regulation-Questionnaire in 106 hypertensive and 106 normotensive patients, enrolled at the Bukavu General Hospital.
Compared with normotensive controls (73% women, age: 43 ± 14 years, BP: 121 ± 10/75 ± 8 mmHg), hypertensive patients (57% women, age: 42 ± 13 years, BP: 141 ± 12/82 ± 7 mmHg, on a median of two antihypertensive drugs) were exposed to more man-made traumas (61 vs. 13%, P < 0.001), used more expressive suppression (P = 0.05) and less cognitive reappraisal (P = 0.02) as emotional regulation strategies. They developed more frequent post-traumatic stress disorder (36 vs. 7%, P < 0.001) and major depressive disorder (37 vs. 13%, P = 0.001), often in association with alcohol use disorder (23 vs. 4%, P < 0.001). In multivariate logistic regression, post-traumatic stress disorder [OR = 3.52 (1.23-6.54)], man-made trauma [OR = 2.24 (1.15-4.12)], family history of hypertension [OR = 2.24 (1.06-4.44)], fasting blood glucose [OR = 1.85 (1.07-3.08)], BMI [OR = 1.28 (1.12-2.92)], expressive suppression [OR = 1.23 (1.11-2.23)] and cognitive reappraisal [OR = 0.76 (0.63-0.98)] were independent predictors of hypertension.
In Congolese populations exposed to war, man-made trauma exposure and post-traumatic stress disorder appear to be more tightly related to hypertension than classical hypertension risk factors.
Keywords
Adult, Case-Control Studies, Depressive Disorder, Major/psychology, Female, Humans, Hypertension/epidemiology, Male, Middle Aged, Stress Disorders, Post-Traumatic/diagnosis, Violence
Pubmed
Web of science
Create date
20/12/2021 12:40
Last modification date
01/04/2022 5:34
Usage data