Diagnostiquer une neuropathie des petites fibres [Small fiber neuropathy diagnosis]

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Version: Final published version
License: CC BY-NC-ND 4.0
Serval ID
serval:BIB_CFEFD75A5BF0
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Diagnostiquer une neuropathie des petites fibres [Small fiber neuropathy diagnosis]
Journal
Revue medicale suisse
Author(s)
Théaudin M., Ochsner F., Adam C., Echaniz-Laguna A., Magy L., Fayolle D., Vicino A., Hübers A., Pereon Y.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
27/04/2022
Peer-reviewed
Oui
Volume
18
Number
779
Pages
803-807
Language
french
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Small fiber neuropathies affect small, poorly myelinated sensory Aδ and amyelinated C autonomic fibers. Neuropathic pain is often the main symptom. Positive diagnosis is based on the presence of deficient thermo-algesic sensory signs and/or dysautonomic signs with normal neurography. Several tests help to confirm the involvement of small fibers, ranging from simple tests such as the sympathetic skin response to skin biopsy, which measures the density of intraepidermal nerve fibers. The availability of these different tests varies greatly from one center to another. There are multiple etiologies, from rare genetic causes to the more frequent acquired dysimmune or metabolic causes. However, in more than half of the cases, no etiology is identified.
Keywords
Biopsy, Humans, Nerve Fibers/pathology, Neuralgia/diagnosis, Neuralgia/etiology, Skin/innervation, Small Fiber Neuropathy/diagnosis, Small Fiber Neuropathy/etiology, Small Fiber Neuropathy/pathology
Pubmed
Create date
16/05/2022 9:55
Last modification date
17/08/2022 6:14
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