The interferon-gamma receptor: a comparison with other cytokine receptors.

Details

Serval ID
serval:BIB_CFA1DA6A7232
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
The interferon-gamma receptor: a comparison with other cytokine receptors.
Journal
Journal of Interferon Research
Author(s)
Aguet M.
ISSN
0197-8357 (Print)
ISSN-L
0197-8357
Publication state
Published
Issued date
1990
Volume
10
Number
6
Pages
551-558
Language
english
Abstract
During the past few years, identification of cytokine receptors has become a major goal in cytokine research. A great deal has been learned from the plethora of receptor structures that have been elucidated recently. Although, evidently, the complexity of the cytokine network extends to the signaling pathways involved, some of these pathways have now become more accessible. The challenge in the coming years will be to fill the gap between the receptors and the gene regulatory events induced by the various cytokines. Another challenge lies in the potential use of cytokine receptors as targets for modulating cytokine action. Since the topic of interferon (IFN) receptors has been reviewed recently, this minireview will focus on the current knowledge on the IFN-gamma receptor in the context of recent advances on other cytokine receptors. Some new receptor models that may be of consequence for characterizing IFN receptors will be presented briefly.
Keywords
Animals, Cytokines/physiology, Humans, Interferons/physiology, Interleukins/physiology, Protein-Tyrosine Kinases/physiology, Receptors, Immunologic/physiology, Receptors, Interferon, Signal Transduction/physiology
Pubmed
Web of science
Create date
28/01/2008 11:36
Last modification date
20/08/2019 15:50
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