Phylogenetic distribution in the genus Mus of t-complex-specific DNA and protein markers: inferences on the origin of t-haplotypes
Details
Serval ID
serval:BIB_CF2D953F281D
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Phylogenetic distribution in the genus Mus of t-complex-specific DNA and protein markers: inferences on the origin of t-haplotypes
Journal
Molecular Biology and Evolution
ISSN
0737-4038 (Print)
Publication state
Published
Issued date
03/1988
Volume
5
Number
2
Pages
120-33
Notes
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Mar
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Mar
Abstract
We have examined the phylogenetic distribution of two t-specific markers among representatives of various taxa belonging to the genus Mus. The centromeric TCP-1a marker (a testicular protein variant specific for all t-haplotypes so far studied) has also been apparently detected in several non-t representatives of the Mus IVA, Mus IVB, and probably M. cervicolor species. By contrast, a t-specific restriction-fragment-length polymorphism allele (RFLP) of the telomeric alpha-globin pseudogene DNA marker alpha-psi-4 was found only in animals belonging to the M. musculus-complex species either bearing genuine t-haplotypes or, like the M. m. bactrianus specimen studied here, likely to do so. This t-specific alpha-psi-4 RFLP allele was found to be as divergent from the RFLP alleles of the latter, non-t, taxonomical groups as it is from Mus 4A, Mus 4B, or M. spretus ones. These results suggest the presence of t-haplotypes and of t-specific markers in populations other than those belonging to the M. m. domesticus and M. m. musculus subspecies, implying a possible origin for t-haplotypes prior to the radiation of the most recent offshoot of the Mus genus (i.e., the spretus/domesticus divergence), some 1-3 Myr ago.
Keywords
Animals
Animals, Wild/genetics
Genetic Markers
Globins/genetics
*Intracellular Signaling Peptides and Proteins
Mice/*genetics
*Microtubule-Associated Proteins
Muridae/genetics
Nuclear Proteins/*genetics
Phylogeny
Polymorphism, Restriction Fragment Length
Pseudogenes
Recombination, Genetic
Species Specificity
Pubmed
Web of science
Create date
25/01/2008 17:17
Last modification date
20/08/2019 16:49