Infantile epileptic encephalopathy (Ohtahara syndrome) and migrational disorder
Details
Serval ID
serval:BIB_CF2C8E6FA05F
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Infantile epileptic encephalopathy (Ohtahara syndrome) and migrational disorder
Journal
Pediatric Neurology
ISSN
0887-8994 (Print)
Publication state
Published
Issued date
1998
Volume
19
Number
1
Pages
50-54
Notes
PT - Case Reports PT - Journal Article
Abstract
A case of early infantile epileptic encephalopathy (EIEE) with suppression-bursts (Ohtahara syndrome) associated with a diffuse cerebral migrational and maturation disorder evident on microscopic examination is reported. Although virtually all reported cases of EIEE are secondary to a congenital or acquired structural malformation of cortical development, EIEE is sometimes identified only by detailed neuropathologic examination, as confirmed by this case report. In addition to the malformation of cortical development, the patient demonstrated an absence of gamma-aminobutyric acid in the cerebrospinal fluid. All children with EIEE should be thoroughly examined by magnetic resonance imaging, cerebrospinal fluid amino acid level determination, and detailed postmortem neuropathologic examination
Keywords
Amygdala/abnormalities/Pathology/Brain Diseases/diagnosis/physiopathology/Cell Movement/physiology/Cerebral Cortex/Choristoma/Electroencephalography/Female/Follow-Up Studies/Humans/Infant/Infant,Newborn/Neuroglia/Neurons/Spasms,Infantile/Syndrome
Pubmed
Web of science
Create date
29/01/2008 19:35
Last modification date
20/08/2019 16:49