Management of fetal tumors.

Details

Serval ID
serval:BIB_CF0E38DA3793
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
Management of fetal tumors.
Journal
Best practice & research. Clinical obstetrics & gynaecology
Author(s)
Masmejan S., Baud D., Ryan G., Van Mieghem T.
ISSN
1532-1932 (Electronic)
ISSN-L
1521-6934
Publication state
Published
Issued date
07/2019
Peer-reviewed
Oui
Volume
58
Pages
107-120
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
In this review article, we discuss the most common fetal tumors, their prenatal management, and outcomes. Overall, the most important outcome predictors are tumor histology, size, vascularity, and location. Very large lesions, lesions causing cardiac failure, and hydrops and lesions obstructing the fetal airway have the poorest outcome, as they may cause fetal death or complications at the time of delivery. Fetal therapy has been developed to improve outcomes for the most severe cases and can consist of transplacental therapy (sirolimus for rhabdomyomas or steroids for hemangiomas and microcystic lung lesions) or surgical intervention (shunting of cystic masses, tumor ablation, occlusion of blood flow or airway exploration, and protection). Given the rarity of fetal tumors, patients should be referred to expert centers where care can be optimized and individualized to allow the best possible outcomes.
Keywords
Fetal therapy, Fetoscopy, Hydrops fetalis, Neoplasms, Shunt
Pubmed
Web of science
Create date
31/03/2019 14:22
Last modification date
01/10/2019 5:09
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