Brief Report: Does Menopause Transition Influence Viral Suppression and Adherence in Women Living With HIV?

Details

Serval ID
serval:BIB_CED2C033D791
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Brief Report: Does Menopause Transition Influence Viral Suppression and Adherence in Women Living With HIV?
Journal
Journal of acquired immune deficiency syndromes
Author(s)
Hachfeld A., Atkinson A., Stute P., Calmy A., Tarr P.E., Darling KEA, Babouee Flury B., Polli C., Sultan-Beyer L., Abela I.A., Aebi-Popp K.
Working group(s)
Swiss HIV Cohort Study (SHCS)
ISSN
1944-7884 (Electronic)
ISSN-L
1525-4135
Publication state
Published
Issued date
15/04/2023
Peer-reviewed
Oui
Volume
92
Number
5
Pages
399-404
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Increasing numbers of women living with HIV transition through menopause. It is unclear whether this transition has an impact on treatment adherence, viral suppression, psychiatric comorbidities, or drug use. We aimed at examining adherence and viral suppression during the perimenopausal period and explored the influence of psychiatric comorbidities and active injection drug use (IDU).
Retrospective Swiss HIV Cohort Study analysis from January 2010 to December 2018.
We explored perimenopausal and postmenopausal trends of viral blips, low-level viremia, viral failure, adherence, psychiatric comorbidities, and IDU using interrupted time series models.
Rates of depression and psychiatric care increased during perimenopause before decreasing afterward. Negative treatment outcomes such as viral blips, low-level viremia, viral failure, and low adherence steadily declined while transitioning through menopause-this was also true for subgroups of women with depression, psychiatric treatment, and active IDU.
Increased rates of depression and psychiatric care while transitioning through menopause do not result in lower rates of adherence or viral suppression in women living with HIV in Switzerland.
Keywords
Humans, Female, Cohort Studies, Anti-HIV Agents/therapeutic use, HIV Infections/complications, HIV Infections/drug therapy, HIV Infections/psychology, Retrospective Studies, Viremia/drug therapy, Menopause, Viral Load
Pubmed
Web of science
Open Access
Yes
Create date
10/01/2023 13:07
Last modification date
18/11/2023 7:09
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