Long term effect of splenectomy on patients operated on for cancer of the left colon: a retrospective study.

Details

Serval ID
serval:BIB_CE2D553B1A2B
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Long term effect of splenectomy on patients operated on for cancer of the left colon: a retrospective study.
Journal
The European journal of surgery = Acta chirurgica
Author(s)
Konstadoulakis M.M., Kymionis G.D., Leandros E., Ricaniadis N., Manouras A., Krespis E., Alexiou D., Androulakis G.
ISSN
1102-4151 (Print)
ISSN-L
1102-4151
Publication state
Published
Issued date
06/1999
Peer-reviewed
Oui
Volume
165
Number
6
Pages
583-587
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
To find out if accidental splenectomy during colonic resection influences the survival of patients with colon cancer.
Retrospective clinical study.
University hospital, Greece.
Twenty-five patients with colonic cancer (13 Dukes' B and 12 Dukes' C) who had accidental splenectomy during resection of the left colon (n = 22) or the sigmoid (n = 3) between 1973 and 1990. Each study patient was matched with control patients for age, sex, Dukes' stage, grade, site of tumour, date, type of operation and number of blood transfusions.
The five year actuarial and disease free survival estimated by the Kaplan-Meier product limit method.
There were significantly more infective postoperative complications (6/25 compared with 0/25, p = 0.02) in patients who had a splenectomy. The incidence of metastases (p = 0.07) and the five-year disease free (p = 0.08) and overall survival (p = 0.1) were lower but not significantly so in patients who had a splenectomy compared with controls.
Splenectomy significantly increases the number of infective postoperative complications in patients with colonic cancer. Although there was a trend for shorter disease-free survival after splenectomy, it seems that splenectomy had no impact on survival.
Keywords
Actuarial Analysis, Aged, Colectomy, Colonic Neoplasms/mortality, Colonic Neoplasms/surgery, Female, Humans, Male, Retrospective Studies, Splenectomy, Surgical Wound Infection/epidemiology, Survival Rate
Pubmed
Web of science
Create date
02/10/2019 9:27
Last modification date
06/10/2019 5:26
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