Blood pressure monitoring in kidney transplantation: a systematic review on hypertension and target organ damage.

Details

Serval ID
serval:BIB_CD36CF663BC5
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Blood pressure monitoring in kidney transplantation: a systematic review on hypertension and target organ damage.
Journal
Nephrology, dialysis, transplantation
Author(s)
Pisano A., Mallamaci F., D'Arrigo G., Bolignano D., Wuerzner G., Ortiz A., Burnier M., Kanaan N., Sarafidis P., Persu A., Ferro C.J., Loutradis C., Boletis I.N., London G., Halimi J.M., Sautenet B., Rossignol P., Vogt L., Zoccali C.
ISSN
1460-2385 (Electronic)
ISSN-L
0931-0509
Publication state
In Press
Peer-reviewed
Oui
Language
english
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Abstract
Sparse studies show that ambulatory blood pressure monitoring (ABPM) is superior to office BP (oBP) measurements to predict target organ damage and cardiovascular (CV) events in kidney transplant recipients (KTRs). We performed a systematic review aimed at determining the potential associations between BP recordings by different methods and renal and CV outcomes in this population.
Major medical databases were searched for studies enrolling adult KTRs undergoing 24h ABPM compared to office or home BP measurements. Main outcomes were: associations between different BP recordings and renal and CV outcomes. Additionally, any association between the circadian BP pattern (dipping/non-dipping status) and outcomes was assessed.
Twenty-two studies (2078 participants) were reviewed. Amongst 12 studies collecting data on renal endpoints, ten studies found that BP assessed by ABPM was a stronger predictor of renal function decline, assessed by serum creatinine (SCr) and/or creatinine clearance (CrCl) or estimated glomerular filtration rate (eGFR), than traditional office measurements. Twelve studies analyzed the relation between different BP recordings and CV target organ damages and reported robust correlations between echocardiographic abnormalities [i.e. left ventricular mass index (LVM/LVMI)] and 24h ABPM, but not with office BPs. Furthermore, 24h ABPM correlated better than oBP with markers of vascular damage, such as carotid intima-media thickness (IMT), diffuse thickening, and endothelial dysfunction. Additionally, abnormal circadian BP pattern (non-dippers and reverse dippers) identified a group of kidney recipients at risk for kidney function loss and CV abnormalities.
In our systematic review, ABPM reflected target organ damage more closely than oBP in KTRs. Furthermore, altered circadian BP profile associated with renal and CV target organ damages.
Keywords
ambulatory blood pressure monitoring, hypertension, kidney transplantation, systematic review, target organ damage
Pubmed
Create date
05/04/2021 10:38
Last modification date
16/07/2021 6:37
Usage data