A fatal case of buflomedil self-poisoning: toxicological data and literature review.

Details

Serval ID
serval:BIB_CCAC562B0F71
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
A fatal case of buflomedil self-poisoning: toxicological data and literature review.
Journal
Forensic Science International
Author(s)
Tracqui A., Deveaux M., Kintz P., Mangin P., Gosset D.
ISSN
0379-0738[print], 0379-0738[linking]
Publication state
Published
Issued date
1995
Volume
71
Number
1
Pages
43-49
Language
english
Abstract
A fatal case of buflomedil (Fonzylane) self-poisoning is presented. Drug identification and quantification in postmortem blood, urine and gastric contents was achieved by means of high pressure liquid chromatography with diode-array detection (HPLC/DAD). Blood concentration was 275 micrograms/ml, > 70 times the usual therapeutic values. Toxicological results are discussed in the light of the existing literature.
Keywords
Adrenergic alpha-Antagonists/pharmacokinetics, Adrenergic alpha-Antagonists/poisoning, Adult, Chromatography, High Pressure Liquid, Depressive Disorder/blood, Depressive Disorder/pathology, Gastrointestinal Contents/chemistry, Humans, Male, Postmortem Changes, Pyrrolidines/pharmacokinetics, Pyrrolidines/poisoning, Suicide/legislation & jurisprudence
Pubmed
Create date
19/10/2010 15:36
Last modification date
20/08/2019 15:47
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