Is cyclophotocoagulation an option in the management of glaucoma secondary to Fuchs' uveitis syndrome?

Details

Serval ID
serval:BIB_CC82A0D235CC
Type
Article: article from journal or magazin.
Collection
Publications
Title
Is cyclophotocoagulation an option in the management of glaucoma secondary to Fuchs' uveitis syndrome?
Journal
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Author(s)
Voykov B., Deuter C., Zierhut M., Leitritz M.A., Guenova E., Doycheva D.
ISSN
1435-702X (Electronic)
ISSN-L
0721-832X
Publication state
Published
Issued date
03/2014
Peer-reviewed
Oui
Volume
252
Number
3
Pages
485-489
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Glaucoma is one of the sight-threatening complications of Fuchs' uveitis syndrome (FUS) and the most difficult to manage. The goal of this study was to assess the efficacy and safety of cyclophotocoagulation (CPC) in the management of glaucoma secondary to FUS.
In a retrospective analysis, the charts of all patients with FUS referred to our clinic from January 2002 to December 2012 were reviewed. In patients with glaucoma or ocular hypertension, controlled eye pressure was defined using two alternative upper limits of 6 ≤ IOP ≤ 21 mmHg and 6 ≤ IOP ≤ 18 mmHg at 1 year follow-up.
One hundred and seventy-six patients with FUS were included in this study. Of those, 28 had ocular hypertension (OHT) or glaucoma. Mean maximal intraocular pressure (IOP) of patients with glaucoma/OHT was 40.8 mmHg. Twenty-three patients (82.1 %) had maximal IOP levels of 35 mmHg or higher. Sixteen patients with glaucoma/OHT underwent CPC alone (ten patients) or in combination with other surgical procedures (six patients). After 1 year, control of IOP for both upper limits (6 ≤ IOP ≤ 18 mmHg) and (6 ≤ IOP ≤ 21 mmHg) was achieved in six of ten patients (60 %) who received CPC alone, and in five of six patients (83.3 %) who required additional surgery after CPC. The mean number of cycloablative procedures was 1.3 (range 1-2) in the CPC alone group and 1.2 (range 1-2) in patients for whom CPC was used as adjunct therapy. There was no exacerbation of intraocular inflammation, no postoperative hypotony and no phthisis bulbi in the 16 patients who underwent CPC.
CPC is a safe and effective procedure that should be considered if medical treatment has failed to control glaucoma in FUS.
Keywords
Adolescent, Adult, Aged, Antihypertensive Agents/therapeutic use, Ciliary Body/surgery, Female, Fuchs' Endothelial Dystrophy/complications, Glaucoma/etiology, Glaucoma/surgery, Humans, Intraocular Pressure, Laser Coagulation, Lasers, Semiconductor/adverse effects, Lasers, Semiconductor/therapeutic use, Male, Middle Aged, Ocular Hypertension/etiology, Ocular Hypertension/surgery, Retrospective Studies, Treatment Failure, Treatment Outcome, Uveitis, Anterior/complications, Young Adult
Pubmed
Web of science
Create date
27/08/2020 14:59
Last modification date
02/09/2020 6:26
Usage data