Sensorimotor Induction of Auditory Misattribution in Early Psychosis

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Serval ID
serval:BIB_CC51E471CFA8
Type
PhD thesis: a PhD thesis.
Collection
Publications
Institution
Title
Sensorimotor Induction of Auditory Misattribution in Early Psychosis
Author(s)
Progin Pierre
Director(s)
Do Kim Q.
Codirector(s)
Blanke Olaf
Institution details
Université de Lausanne, Faculté de biologie et médecine
ISSN
0586-7614
1745-1701
Publication state
Accepted
Issued date
08/07/2020
Language
english
Abstract
Dysfunction of sensorimotor predictive processing is thought to underlie abnormalities in self-monitoring producing passivity symptoms in psychosis. Experimentally induced sensorimotor conflict can produce a failure in bodily self-monitoring (presence hallucination [PH]), yet it is unclear how this is related to auditory self-monitoring and psychosis symptoms. Here we show that the induction of sensorimotor conflict in early psychosis patients induces PH and impacts auditory-verbal self-monitoring. Participants manipulated a haptic robotic system inducing a bodily sensorimotor conflict. In experiment 1, the PH was measured. In experiment 2, an auditory-verbal self-monitoring task was performed during the conflict. Fifty-one participants (31 early psychosis patients, 20 matched controls) participated in the experiments. The PH was present in all participants. Psychosis patients with passivity experiences (PE+) had reduced accuracy in auditory-verbal self-other discrimination during sensorimotor stimulation, but only when sensorimotor stimulation involved a spatiotemporal conflict (F(2, 44) = 6.68, P = .002). These results show a strong link between robotically controlled alterations in sensorimotor processing and auditory misattribution in psychosis and provide evidence for the role of sensorimotor processes in altered self-monitoring in psychosis.
Create date
29/09/2020 18:13
Last modification date
04/03/2021 7:26
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