Improvement of left ventricular function after percutaneous transluminal coronary angioplasty
Details
Serval ID
serval:BIB_CC00D335B17E
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Improvement of left ventricular function after percutaneous transluminal coronary angioplasty
Journal
American Journal of Cardiology
ISSN
0002-9149 (Print)
Publication state
Published
Issued date
03/1982
Volume
49
Number
4
Pages
651-657
Notes
Journal Article --- Old month value: Mar
Abstract
Cardiac function and left ventricular dynamics were measured in seven consecutive patients 1 day before and 6 months after percutaneous transluminal balloon angioplasty of subtotal proximal stenosis of the left anterior descending coronary artery. Before angioplasty all patients had obvious left ventricular dysfunction during exercise and to a smaller degree during isoproterenol infusion; the condition of all patients was greatly improved 6 months after angioplasty. After angioplasty, left ventricular end-diastolic pressure was normal at rest and decreased from a mean (+/- standard error of the mean) of 33.8 +/- 1.6 to 19.2 +/- 0.5 mm Hg on exercise. Left ventricular ejection fraction, measured by a gated blood pooling technique with technetium-99m, improved on exercise from 46 +/- 5.0 percent to 69 +/- 1.0 percent. Cardiac output and stroke volume index increased significantly with exercise after angioplasty. The peak negative rate of pressure reduction in the left ventricle (dP/dt/min), an index of left ventricular relaxation, was highly abnormal on exercise before (2,307 +/- 260 mm Hg/s) and increased to the normal range (3,154 +/- 200 mm Hg/s) after angioplasty. The improvement in left ventricular function after transluminal angioplasty in these cases of proximal left anterior descending coronary arterial stenosis is extremely encouraging.
Keywords
Adult Cardiac Output Catheterization Coronary Disease/*surgery Coronary Vessels/*surgery Heart Ventricles/physiopathology Hemodynamic Processes Humans Male Middle Aged *Myocardial Contraction Prognosis
Pubmed
Web of science
Create date
25/01/2008 12:22
Last modification date
20/08/2019 16:46