Protein metabolism and postnatal growth in very low birthweight infants.

Details

Serval ID
serval:BIB_CBEFDAF23959
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Protein metabolism and postnatal growth in very low birthweight infants.
Journal
Biology of the Neonate
Author(s)
Micheli J.L., Schutz Y.
ISSN
0006-3126 (Print)
ISSN-L
0006-3126
Publication state
Published
Issued date
1987
Volume
52 Suppl 1
Pages
25-40
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Due to the development of new 'bedside' investigative methods, relatively abstract physiologic concepts such as energy cost of growth, efficiency of protein gain, metabolic cost of protein gain and protein turnover have been quantified in very low birthweight infants. 'Healthy' premature infants expend about 30% of their energy to cover the metabolic cost of growth. Stable isotope techniques using 15N-(or 13C)-labeled amino acids gave a new insight into this very high energy demanding process represented by the protein accretion in growing tissues. It has been demonstrated that the rate of protein synthesis (10-12 g/kg/day) greatly exceeds that necessary for net protein gain (2 g/kg/day). The postnatal growth and protein metabolism have different characteristics in 'healthy', 'sick' or 'intrauterine undernourished' very low birthweight infants.
Keywords
Energy Metabolism, Humans, Infant, Low Birth Weight/growth & development, Infant, Low Birth Weight/metabolism, Infant, Newborn, Nutritional Requirements, Proteins/metabolism
Pubmed
Web of science
Create date
21/01/2008 14:08
Last modification date
20/08/2019 16:46
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