Infection and Pediatric Arterial Ischemic Stroke Presumably Related to Focal Cerebral Arteriopathy: Data From the COVID-19 Pandemic.

Details

Ressource 1Request a copy Under indefinite embargo.
UNIL restricted access
State: Public
Version: Final published version
License: Not specified
Secondary document(s)
Under indefinite embargo.
UNIL restricted access
State: Public
Version: Supplementary document
License: Not specified
Under indefinite embargo.
UNIL restricted access
State: Public
Version: Supplementary document
License: Not specified
Serval ID
serval:BIB_CB96F3AAD8D3
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Infection and Pediatric Arterial Ischemic Stroke Presumably Related to Focal Cerebral Arteriopathy: Data From the COVID-19 Pandemic.
Journal
Stroke
Author(s)
Tudorache R., Jaboyedoff M., Gabet A., Olié V., Angoulvant F., Tuppin P., Lesuffleur T., Kossorotoff M.
ISSN
1524-4628 (Electronic)
ISSN-L
0039-2499
Publication state
Published
Issued date
06/2024
Peer-reviewed
Oui
Volume
55
Number
6
Pages
1672-1675
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Infection may trigger pediatric arterial ischemic stroke (PAIS), notably when related to focal cerebral arteriopathy. Community- and individual-level nonpharmaceutical interventions during the COVID-19 pandemic resulted in a major decrease in pediatric viral infections. We explored the consequences on the incidence of PAIS.
Using national public health databases, we identified children hospitalized between 2015 and 2022 with PAIS. Using an age proxy (29 days to 7 years) and excluding patients with cardiac and hematologic conditions, we focused on children with PAIS presumably related to focal cerebral arteriopathy or with no definite cause. Considering the delay between infection and PAIS occurrence, we compared a prepandemic reference period, a period with nonpharmaceutical interventions, and a post-nonpharmaceutical intervention period.
Interrupted time-series analyses of the monthly incidence of PAIS in this group showed a significant decrease in the nonpharmaceutical intervention period compared with the prepandemic period: -33.5% (95% CI, -55.2%, -1.3%); P=0.043.
These data support the association between infection and PAIS presumably related to focal cerebral arteriopathy.
Keywords
Humans, COVID-19/epidemiology, COVID-19/complications, Ischemic Stroke/epidemiology, Child, Child, Preschool, Infant, Male, Female, Incidence, Infant, Newborn, SARS-CoV-2, Pandemics, Cerebral Arterial Diseases/epidemiology, Adolescent, Interrupted Time Series Analysis, COVID-19, child, incidence, ischemic stroke, public health
Pubmed
Web of science
Create date
14/06/2024 12:11
Last modification date
26/07/2024 7:02
Usage data