Personality as a Predictor of Disability in Multiple Sclerosis.

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State: Public
Version: Final published version
License: CC BY-NC 4.0
Serval ID
serval:BIB_CB7C03C5B33A
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Personality as a Predictor of Disability in Multiple Sclerosis.
Journal
Archives of clinical neuropsychology
Author(s)
Jacot de Alcântara I., Voruz P., Allali G., Fragnoli C., Antoniou M.P., Lalive P.H., Péron J.A.
ISSN
1873-5843 (Electronic)
ISSN-L
0887-6177
Publication state
Published
Issued date
25/07/2023
Peer-reviewed
Oui
Volume
38
Number
5
Pages
657-666
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
As personality changes and personality disorders are frequently observed in multiple sclerosis (MS), personality may be a prognostic factor for this disease. The present study investigated the influence of personality on disability, progression, and treatment adherence in MS.
Personality was assessed in 41 patients with Relapsing-Remitting MS (30 females; mean age = 42.63 years) using the NEO Personality Inventory-3rd edition. Disability was measured with the Expanded Disability Status Scale, and treatment adherence information was collected from the Swiss MS Cohort. Correlation, multiple linear and partial least square regressions were performed to examine relations between personality, disability, and treatment adherence in MS.
After accounting for age and time since disease onset, our analysis revealed that Neuroticism (β = 0.32, p = 0.01) and its Vulnerability facet (β = 0.28, p < 0.05) predicted greater disability, whereas Extraversion (β = -0.25, p = 0.04) and its Activity facet (β = -0.23, p < 0.05) predicted milder disability. Regarding disability progression, correlational analysis revealed that it was negatively correlated with Extraversion (r = -0.44, p = 0.02) and the Feelings facet of Openness (r = -0.41, p = 0.03), but regressions failed to highlight any predictive links. No significant results could be demonstrated for treatment adherence.
Overall, our study showed that some personality traits can impact disability in MS, indicating that these should be considered in clinical practice, as they could be used to adapt and improve patients' clinical support.
Keywords
Female, Humans, Adult, Multiple Sclerosis/complications, Neuropsychological Tests, Personality, Multiple Sclerosis, Relapsing-Remitting, Personality Disorders/diagnosis, Personality Disorders/etiology, Disability/handicaps, Multiple sclerosis, Personality and personality disorders
Pubmed
Web of science
Open Access
Yes
Create date
03/03/2023 17:06
Last modification date
03/10/2023 7:15
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