Intranasal trigeminal function in patients with empty nose syndrome.

Details

Serval ID
serval:BIB_CB40E815C413
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Intranasal trigeminal function in patients with empty nose syndrome.
Journal
The Laryngoscope
Author(s)
Konstantinidis I., Tsakiropoulou E., Chatziavramidis A., Ikonomidis C., Markou K.
ISSN
1531-4995 (Electronic)
ISSN-L
0023-852X
Publication state
Published
Issued date
06/2017
Peer-reviewed
Oui
Volume
127
Number
6
Pages
1263-1267
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Trigeminal nerve mediates the perception of nasal airflow. This study examines whether impaired intranasal trigeminal function is a part of the paradoxical nasal obstruction sensation in patients with empty nose syndrome (ENS).
Prospective case-control study in a tertiary hospital.
Three groups were examined: 1) ENS patients with previous bilateral near total inferior turbinectomy, 2) patients who underwent near total inferior turbinate removal (ITR) without ENS symptoms, and 3) control participants. All participants examined with active anterior rhinomanometry, olfactory testing (extended Sniffin' Sticks test), and trigeminal testing (lateralization task using menthol and odorless solvent).
Seventy-one participants were included (21 ENS patients, 18 ITR patients, and 31 controls). Analyses revealed that ENS patients had significantly lower scores on trigeminal lateralization testing than the ITR group and controls. The ENS group had also significantly lower scores in olfactory testing than controls. No statistical differences were found in rhinomanometry between groups. The gender factor was not associated with the chemosensory testing; however, this was not the case with the age factor, as trigeminal test results were negatively correlated.
This study demonstrates significantly impaired intranasal trigeminal function in ENS patients when compared with ITR patients and controls. Further prospective studies are needed to clarify the role of preoperative trigeminal function of these patients and the contribution of surgery to this impairment.
3b. Laryngoscope, 127:1263-1267, 2017.

Keywords
Adult, Age Factors, Case-Control Studies, Female, Humans, Male, Menthol, Middle Aged, Nasal Obstruction/complications, Nasal Obstruction/physiopathology, Olfaction Disorders/etiology, Olfaction Disorders/physiopathology, Prospective Studies, Rhinomanometry, Smell/physiology, Solvents, Syndrome, Trigeminal Nerve/physiopathology, Turbinates/surgery, Young Adult, Trigeminal nerve, empty nose syndrome, olfaction, turbinectomy
Pubmed
Web of science
Create date
28/02/2017 18:30
Last modification date
20/08/2019 15:46
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