Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain.

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Serval ID
serval:BIB_CB3D210CEC47
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Single spin-echo T 2 relaxation times of cerebral metabolites at 14.1 T in the in vivo rat brain.
Journal
Magma
Author(s)
Xin L., Gambarota G., Cudalbu C., Mlynárik V., Gruetter R.
ISSN
0968-5243 (Print)
ISSN-L
0968-5243
Publication state
Published
Issued date
2013
Peer-reviewed
Oui
Volume
26
Number
6
Pages
549-554
Language
english
Notes
Publication types: Journal Article Publication Status: ppublish. PDF type: research article
Abstract
OBJECT: To determine the single spin-echo T 2 relaxation times of uncoupled and J-coupled metabolites in rat brain in vivo at 14.1 T and to compare these results with those previously obtained at 9.4 T.
MATERIALS AND METHODS: Measurements were performed on five rats at 14.1 T using the SPECIAL sequence and TE-specific basis-sets for LCModel analysis.
RESULTS AND CONCLUSION: The T 2 of singlets ranged from 98 to 148 ms and T 2 of J-coupled metabolites ranged from 72 ms (glutamate) to 97 ms (myo-inositol). When comparing the T 2s of the metabolites measured at 14.1 T with those previously measured at 9.4 T, a decreasing trend was found (p < 0.0001). We conclude that the modest shortening of T 2 at 14.1 T has a negligible impact on the sensitivity of the (1)H MRS when performed at TE shorter than 10 ms.
Pubmed
Web of science
Open Access
Yes
Create date
29/04/2013 11:52
Last modification date
01/10/2019 6:19
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