Role of microRNA in pancreatic beta cell function

Details

Serval ID
serval:BIB_CAE8B483616B
Type
A part of a book
Publication sub-type
Chapter: chapter ou part
Collection
Publications
Institution
Title
Role of microRNA in pancreatic beta cell function
Title of the book
Pancreatic ß-Cell Biology in Health and Disease
Author(s)
Brozzi Flora
Publisher
Elsevier
ISBN
9780128237557
ISSN
1937-6448
ISSN-L
1937-6448
Publication state
Published
Issued date
2021
Peer-reviewed
Oui
Volume
359
Pages
257-286
Language
english
Abstract
MicroRNA (miRNAs) are small non-coding RNA involved in gene expression regulation. Emerging evidences identify miRNAs as key regulators of beta cell physiology. Their role in fine-tuned gene expression regulation is crucial in the differentiation of insulin-producing cells and contributes to the acquisition and management of their unique phenotype. Dysregulation of miRNA expression causes beta cell dysfunction and promotes the development of different forms of diabetes mellitus.
Keywords
Beta cell functions, Islets of Langerhans, Non-coding RNA, Pancreatic beta cells, Type 1 diabetes, Type 2 diabetes, miRNA
Pubmed
Web of science
Create date
04/05/2021 9:32
Last modification date
20/12/2023 8:14
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