High signal intensity on T2-weighted MRI correlates with hypoperfusion in temporal lobe epilepsy

Details

Serval ID
serval:BIB_CAAB30FAD02B
Type
Article: article from journal or magazin.
Collection
Publications
Title
High signal intensity on T2-weighted MRI correlates with hypoperfusion in temporal lobe epilepsy
Journal
Epilepsia
Author(s)
Ryvlin P., Garcia-Larrea L., Philippon B., Froment J. C., Fischer C., Revol M., Mauguiere F.
ISSN
0013-9580 (Print)
ISSN-L
0013-9580
Publication state
Published
Issued date
1992
Volume
33
Number
1
Pages
28-35
Language
english
Notes
Ryvlin, P
Garcia-Larrea, L
Philippon, B
Froment, J C
Fischer, C
Revol, M
Mauguiere, F
eng
Epilepsia. 1992 Jan-Feb;33(1):28-35.
Abstract
Single-photon emission computed tomography (SPECT) and [99mTc]HMPAO were used to assess the functional significance of nonspecific magnetic resonance imaging (MRI) abnormalities observed in patients with temporal lobe epilepsy and no focal lesion on CT scan. We studied 18 patients whose MRI was normal or showed high signal intensity on T2-weighted images (T2WIs) at the site of the EEG focus in 11 and 7 cases, respectively. EEG was monitored during regional cerebral blood flow (rCBF) study. Lateralized hypoperfusion was present in 7 of 17 interictal (41%) and in one postictal cases; it was located in the temporal lobe on the side of the EEG focus in all, and was significantly more frequent in patients with high signal intensity on T2WI (86%) than in patients with a normal MRI (18%). The degree of temporal perfusion asymmetry measured in each individual was higher in patients whose MRI was abnormal.
Keywords
Adolescent, Adult, Cerebrovascular Circulation, Electroencephalography, Epilepsy, Temporal Lobe/*diagnosis/physiopathology, Female, Humans, *Magnetic Resonance Imaging, Male, Middle Aged, Organotechnetium Compounds, Oximes, Technetium Tc 99m Exametazime, Temporal Lobe/*blood supply, *Tomography, Emission-Computed, Single-Photon
Pubmed
Create date
29/11/2018 13:37
Last modification date
20/08/2019 16:45
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