Effect of menstrual cycle phase on physiological responses in healthy women at rest and during submaximal exercise at high altitude.
Details
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State: Public
Version: author
License: CC BY 4.0
UNIL restricted access
State: Public
Version: author
License: CC BY 4.0
Serval ID
serval:BIB_CA7705430B19
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Effect of menstrual cycle phase on physiological responses in healthy women at rest and during submaximal exercise at high altitude.
Journal
Scientific reports
ISSN
2045-2322 (Electronic)
ISSN-L
2045-2322
Publication state
Published
Issued date
13/11/2024
Peer-reviewed
Oui
Volume
14
Number
1
Pages
27793
Language
english
Notes
Publication types: Journal Article
Publication Status: epublish
Publication Status: epublish
Abstract
As more women engage in high-altitude activities, understanding how ovarian hormone fluctuations affect their cardiorespiratory system is essential for optimizing acclimatization to these environments. This study investigates the effects of menstrual cycle (MC) phases on physiological responses at rest, during and after submaximal exercise, at high-altitude (barometric pressure 509 ± 6 mmHg; partial pressure of inspired oxygen 96 ± 1 mmHg; ambient temperature 21 ± 2 °C and relative humidity 27 ± 4%) in 16 eumenorrheic women. Gas exchange, hemodynamic responses, heart rate variability and heart rate recovery (HRR) were monitored at low altitude, and then at 3375 m on the Mont Blanc (following nocturnal exposure) during both the early-follicular (EF) and mid-luteal (ML) phases. Significant differences were observed between low and high-altitude in ventilation, heart rate and cardiac output. Resting ventilation (15.2 ± 1.9 vs. 13.2 ± 2.5 L.min <sup>-1</sup> ; p = 0.039) and tidal volume (812 ± 217 vs. 713 ± 190 mL; p = 0.027) were higher during EF than ML at high-altitude. These differences between EF and ML were no longer evident during exercise, with comparable responses in oxygen uptake kinetics, cycling efficiency and HRR. The MC had negligible effects on physiological responses to high-altitude. An individualized approach, tailored to each woman's specific responses to hypoxia across the MC, may be more beneficial in optimizing high-altitude sojourns than general guidelines.
Keywords
Humans, Female, Altitude, Exercise/physiology, Adult, Heart Rate/physiology, Menstrual Cycle/physiology, Rest/physiology, Young Adult, Hemodynamics/physiology, Oxygen Consumption/physiology, Acclimatization/physiology, Pulmonary Gas Exchange/physiology, Cardiac Output/physiology, Acute high-altitude exposure, Cardiorespiratory, Net efficiency, Ovarian hormone fluctuations, Post-exercise recovery
Pubmed
Open Access
Yes
Create date
18/11/2024 12:07
Last modification date
22/11/2024 17:55