Structural profile of dome-shaped macula in degenerative myopia and its association with macular disorders.

Details

Serval ID
serval:BIB_CA67E5503464
Type
Article: article from journal or magazin.
Collection
Publications
Title
Structural profile of dome-shaped macula in degenerative myopia and its association with macular disorders.
Journal
BMC ophthalmology
Author(s)
Lee G.W., Kim J.H., Kang S.W., Kim J.
ISSN
1471-2415 (Electronic)
ISSN-L
1471-2415
Publication state
Published
Issued date
24/05/2020
Peer-reviewed
Oui
Volume
20
Number
1
Pages
202
Language
english
Notes
Publication types: Journal Article ; Observational Study
Publication Status: epublish
Abstract
To evaluate the detailed structural profile of dome-shaped macula and its association with myopic macular complications.
This retrospective study included 147 eyes of 93 patients who were diagnosed with degenerative myopia. The height of the scleral dome and diameter of the dome base were measured via enhanced depth imaging optical coherence tomography images with 1:1 μm setting. Spherical equivalent and best-corrected visual acuity were compared in eyes with and without dome-shaped macula. In eyes with dome-shaped macula, the height and diameter of the dome were compared in eyes with and without myopic macular complications including choroidal neovascularization, myopic foveoschisis, and macular hole.
Dome-shaped macula was noted in 60 eyes (40.8%) of 42 patients. The mean height of the dome in the eyes with dome-shaped macula was 126.5 ± 69.4 μm (53 to 345 μm) and the mean diameter of the dome base was 2862.1 ± 794.9 μm (1567 μm to 4886 μm). In comparing eyes with and without dome-shaped macula, eyes with dome-shaped macula had higher myopia (- 13.7 diopters vs - 12.1 diopters, P = 0.022). There was no difference in visual acuity in eyes with or without dome-shaped macula (P = 0.132). The height and diameter of the dome in eyes with and without myopic foveoschisis were 78.6 ± 20.6 μm and 134.9 ± 71.6 μm, 2499.2 ± 303.1 μm and 2969.3 ± 645.7 μm, respectively (P = 0.009 and P = 0.017). However, the height and diameter of the dome were not related to the incidence of a macular hole (P = 0.324 and P = 0.605) and choroidal neovascularization (P = 0.835 and P = 0.905).
The prevalence of dome-shaped macula was about 40% in the eyes with degenerative myopia. Although dome-shaped macula was associated with higher degrees of myopia, a prominent dome seemed to be protective against myopic foveoschisis.
Keywords
Female, Fluorescein Angiography/methods, Fundus Oculi, Humans, Macula Lutea/pathology, Male, Middle Aged, Myopia, Degenerative/complications, Myopia, Degenerative/diagnosis, Retinal Diseases/diagnosis, Retinal Diseases/etiology, Retrospective Studies, Tomography, Optical Coherence/methods, Visual Acuity, Degenerative myopia, Dome-shaped macula, Myopic foveoschisis
Pubmed
Web of science
Open Access
Yes
Create date
10/03/2022 8:44
Last modification date
11/03/2022 6:33
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