Candida glabrata spinal osteomyelitis involving two contiguous lumbar vertebrae: a case report and review of the literature
Details
Serval ID
serval:BIB_CA1CEAABF534
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Candida glabrata spinal osteomyelitis involving two contiguous lumbar vertebrae: a case report and review of the literature
Journal
Diagnostic Microbiology and Infectious Disease
ISSN
0732-8893 (Print)
Publication state
Published
Issued date
02/2003
Volume
45
Number
2
Pages
137-41
Notes
Case Reports
Journal Article --- Old month value: Feb
Journal Article --- Old month value: Feb
Abstract
Due to the increase of the immunocompromised population, mucosal and systemic infections caused by Candida glabrata, formerly known as Torulopsis glabrata, have shown a recent significant increase. We present a case of C. glabrata vertebral osteomyelitis which required repeated surgical therapy, a complete L2 and L3 corporectomy and more than one year of hospitalisation to complete healing. We compare this case to eight previously reported cases outlining the features of C. glabrata spinal osteomyelitis, including symptoms, diagnosis, treatment, evolution and outcome. According to the case presented and in review of the literature, we believe that in the absence of abscess and neurologic symptoms, medical treatment should be initiated with close clinical, laboratory and radiologic follow-up. An unfavorable evolution of these parameters should be an indication for aggressive and, if necessary, repeated surgical intervention in association with an antifungal treatment.
Keywords
Amphotericin B/therapeutic use
*Candida glabrata/pathogenicity
Candidiasis/*diagnosis/surgery/*therapy
Fluconazole/therapeutic use
Humans
*Lumbar Vertebrae/pathology/radiography
Male
Osteomyelitis/*diagnosis/microbiology/*therapy
Pubmed
Web of science
Create date
25/01/2008 14:33
Last modification date
20/08/2019 16:45