Laparoscopic partial hepatectomy in the rat: a new resectional technique.
Details
State: Public
Version: Final published version
License: Not specified
Serval ID
serval:BIB_C90CF10CC8AE
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Laparoscopic partial hepatectomy in the rat: a new resectional technique.
Journal
Digestive surgery
ISSN
0253-4886 (Print)
ISSN-L
0253-4886
Publication state
Published
Issued date
1998
Peer-reviewed
Oui
Volume
15
Number
2
Pages
140-144
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
Rats are widely used for basic research in laparoscopic surgery. We have developed a new technique of laparoscopic partial hepatectomy in the rat.
40 American Cancer Institute rats were randomized into 3 groups. Group A (n = 14) underwent laparoscopic liver resection using a CO2 pneumoperitoneum. Group B (n = 14) was operated on with a gasless laparoscopic technique using a lifting device. A control group C (n = 12) underwent conventional open liver resection. In each group half of the animals underwent single lobectomy and the other half bilobectomy.
The liver resection was performed successfully in all 40 rats. No conversion to open surgery was necessary. No mortality or morbidity was observed.
This new technique of laparoscopic partial hepatectomy proved to be feasible and safe. It is the first description of a laparoscopic hepatic resection in the rat that could prove valuable in further investigations of liver physiology and pathology.
40 American Cancer Institute rats were randomized into 3 groups. Group A (n = 14) underwent laparoscopic liver resection using a CO2 pneumoperitoneum. Group B (n = 14) was operated on with a gasless laparoscopic technique using a lifting device. A control group C (n = 12) underwent conventional open liver resection. In each group half of the animals underwent single lobectomy and the other half bilobectomy.
The liver resection was performed successfully in all 40 rats. No conversion to open surgery was necessary. No mortality or morbidity was observed.
This new technique of laparoscopic partial hepatectomy proved to be feasible and safe. It is the first description of a laparoscopic hepatic resection in the rat that could prove valuable in further investigations of liver physiology and pathology.
Keywords
Animals, Carbon Dioxide, Disease Models, Animal, Feasibility Studies, Hepatectomy/methods, Laparoscopy/methods, Male, Pneumoperitoneum, Artificial/methods, Random Allocation, Rats
Pubmed
Web of science
Open Access
Yes
Create date
11/12/2018 11:53
Last modification date
09/05/2023 8:47
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